Autism linked to hundreds of genetic changes

Yale researchers discover many genetic keys needed to unlock autism – Investigating 1,000 families reveals hundreds of small genetic variations are associated with autism spectrum disorders, according to a multi-site collaborative study led by researchers at Yale University. These genetic findings can be used to begin unraveling the underlying biology of autism.

Brain senses fatty food

Researchers have identified a molecule that tells your brain your stomach is full ? signaling that it’s time to say no to a second piece of pumpkin pie and push back from the Thanksgiving table. – In the battle against obesity, Yale University researchers may have discovered a new weapon – a naturally occurring molecule secreted by the gut that makes rats and mice less hungry after fatty meals.

Genes, lower reward response linked to weight gain, obesity

Yale researchers tie genes, lower reward response to weight gain and obesity. – The brains of obese people seem to respond to a tasty treat with less vigor than the brains of their leaner peers, suggesting obese people may overeat to compensate for a reduced reward response, according to a new brain imaging and genetics study conducted by researchers at Yale University, The John B. Pierce Laboratory, the University of Texas and Oregon Research Institute.

Stomach bacteria protect against type 1 diabetes

Friendly? bacteria in stomach protect against type 1 diabetes, Yale researchers find. – In a dramatic illustration of the potential for microbes to prevent disease, researchers at Yale University and the University of Chicago showed that mice exposed to common stomach bacteria were protected against the development of Type I diabetes.

Two more Autism Centers of Excellence funded

New NIH funding for two Autism Centers of Excellence — A total of 11 centers now funded for up to five years – The National Institutes of Health has awarded $5.3 million in initial one-year funding to the latest two recipients of the Autism Centers of Excellence (ACE) program. With these awards, announced on World Autism Awareness Day, these and nine other ACE centers in US are now being funded for up to five years.

Alcohol helps accelerate brains of heavy drinkers

Enhanced brain acetate metabolism may reward heavy drinkers – Increased brain uptake and oxidation of acetate in heavy drinkers – In addition to its well-known effects on the CNS, alcohol consumption has a significant impact on metabolism. After consumption, the body rapidly begins converting ethanol to acetate, which can serve as an energy source for the brain and other organs.

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