Type 2 diabetes genes associated with prostate cancer

Six new genes identified which play a role in the development of type 2 diabetes, and among the group is the second gene known to also play a role in prostate cancer. – Scientists have identified six new genes which play a role in the development of type 2 diabetes, and among the group is the second gene known to also play a role in prostate cancer.

Race differences affect response to drugs and infections

Gene expression differences between those of European and African ancestry affect response to drugs and infections. – Differences in gene expression levels between people of European versus African ancestry can affect how each group responds to certain drugs or fights off specific infections, report researchers from the University of Chicago Medical Center and the Expression Research Laboratory at Affymetrix Inc. of Santa Clara, CA.

New chemical tool kit reveals insights into drug toxicity

A Harvard Medical School team led by Vamsi Mootha has developed a new chemical tool kit that helps in explaining how drugs can affect its users, reveals insights into drug toxicity. – Why do nearly 1 million people taking cholesterol-lowering statins often experience muscle cramps? Why is it that in the rare case when a diabetic takes medication for intestinal worms, his glucose levels improve? Is there any scientific basis for the purported health effects of green tea?

7 new prostate cancer genetic risk factors identified

UK researchers identified more than 7 new genetic links to prostate cancer, 2 of which would be included in a new diagnostic test aimed at spotting men at risk from this disease. – 7 new sites in the human genome identified that are linked to men’s risk of developing prostate cancer, revealed by Cancer Research UK funded scientists at the Institute of Cancer Research and University of Cambridge.

IGFBP7 protein may stop melanoma skin cancer

One might call it a tale of two melanocytes. Given the same genetic mutation, why does one melanocyte shut down growth and become a relatively benign mole, while another rages out of control and develops into deadly melanoma” – Howard Hughes Medical Institute (HHMI) researchers have uncovered a protein that stops the growth of melanoma, a cancer that develops from pigment-producing cells in the skin called melanocytes.

Genes linked with lupus giving hope for new treatments

Researchers have made a number of important new discoveries into the mysterious autoimmune disease lupus. A consortium of international researchers has located new regions of the human genome associated with an increased risk for the disease. – Scientists have identified a number of genes involved in Lupus, a devastating autoimmune disease, in new research published today in the journal Nature Genetics. In an international genetic study of more than 3,000 women, researchers found evidence of an association between Lupus (systemic lupus erythematosus or SLE) and mutations in several different genes.

Studies highlight MRSA evolution and resilience

A single strain of an evolving bacterium has been responsible for most of the community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) infections. – Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) infections are caused primarily by a single strain-USA300-of an evolving bacterium that has spread with “extraordinary transmissibility” throughout the United States during the past five years, according to a new study led by National Institutes of Health (NIH) scientists. CA-MRSA, an emerging public health concern, typically causes readily treatable soft-tissue infections such as boils, but also can lead to life-threatening conditions that are difficult to treat.

Chromosomal abnormalities play substantial role in autism

Chromosomal abnormalities play substantial role in autism, revealed in a study. Noting this change would help early diagnosis for autism or autism spectrum disorder (ASD) – a kind of developmental disorder. – Genome-wide scans of families affected by autism spectrum disorder (ASD) have revealed new evidence that previously unknown chromosomal abnormalities have a substantial role in the prevalent developmental disorder, according to a report published online Jan. 17th in the American Journal of Human Genetics, a publication of Cell Press.

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