Anti inflammatory drugs reduce effectiveness of SSRI antidepressants

Anti-inflammatory drugs reduce effectiveness of SSRI antidepressants – Anti-inflammatory drugs, which include ibuprofen, aspirin and naproxen, reduce the effectiveness of the most widely used class of antidepressant medications, the selective serotonin reuptake inhibitors, or SSRIs, taken for depression and obsessive-compulsive disorder and anxiety disorders.

Nytol, Benadryl, Ditropan and Piriton raising dementia risk

Dementia ‘linked’ to common over-the-counter drugs — Hayfever drugs raise risk of Alzheimer’s disease, say scientists – Over-the counter hayfever tables, sleeping pills or asthma drugs significantly raise the risk of developing dementia, a study has shown.

Paradoxical effect of certain antidepressants discovered

Why some antidepressants may initially worsen symptoms – New research helps explain a paradoxical effect of certain antidepressants–that they may actually worsen symptoms before helping patients feel better. These findings may help investigators fix the problem as well as create new classes of drugs to treat depression.

Antidepressant may prevent heart failure

Popular antidepressant might prevent heart failure – A medication usually used to help treat depression and anxiety disorders has the potential to help prevent heart failure. John Tesmer, research professor at the U-M Life Sciences Institute and professor in the Department of Pharmacology at the U-M Medical School, and his research team at the Tesmer lab found that paroxetine, a selective serotonin reuptake inhibitor (SSRI) sold under the name Paxil, inhibits G protein-coupled receptor kinase 2 (GRK2), a protein kinase that becomes over-expressed when people have heart failure.

Two genes TPH1 and TPH2 more likely to develop PTSD symptoms

PTSD genes identified by UCLA study — Findings could lead to new screenings, targeted therapies — Two genes TPH1 and TPH2 more likely to develop PTSD symptoms – Why do some persons succumb to post-traumatic stress disorder (PTSD) while others who suffered the same ordeal do not? UCLA scientists have linked two genes involved in serotonin production to a higher risk of developing PTSD.

Antidepressants may not improve all symptoms of depression

Antidepressants may not improve all symptoms of depression, UT Southwestern researchers find – Even people who show a clear treatment response with antidepressant medications continue to experience symptoms like insomnia, sadness and decreased concentration, researchers at UT Southwestern Medical Center have found after analyzing data from the largest study on the treatment of depression.

Antidepressant may reduce menopausal hot flashes

Use of Antidepressant Associated With Reduction in Menopausal Hot Flashes – Women who were either in the transition to menopause or postmenopausal experienced a reduction in the frequency and severity of menopausal hot flashes with the use of the antidepressant medication escitalopram, compared to women who received placebo.

Lack of evidence for antidepressants in Autism

Autism: Lack of evidence for antidepressants – Antidepressants commonly prescribed to people with autistic spectrum disorders cannot be recommended based on current evidence, revealed by Cochrane Researchers.

New target for antidepressants for depression and anxiety

Animal study reveals new target for antidepressants – University of Michigan scientists have provided the most detailed picture yet of a key receptor in the brain that influences the effectiveness of serotonin-related antidepressants, such as Prozac.

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