Binge drinking increases cognitive decline in older adults

Binge drinking increases the risk of cognitive decline in older adults – Researchers from the Peninsula College of Medicine and Dentistry (PCMD), University of Exeter, suggesting a link between binge drinking in older adults and the risk of developing dementia. The work is supported by the National Institute for Health Research Collaboration for Leadership in Applied Health Research and Care in the South West Peninsula (NIHR PenCLAHRC).

Alzheimer’s Disease timeline invaluable for successful drug trials

First detailed timeline established for brain’s descent into Alzheimer’s – Scientists have assembled the most detailed chronology to date of the human brain’s long, slow slide into full-blown Alzheimer’s disease. As part of an international research partnership known as the Dominantly Inherited Alzheimer’s Network (DIAN), scientists at Washington University and elsewhere evaluated a variety of pre-symptomatic markers of Alzheimer’s disease in 128 subjects from families genetically predisposed to develop the disorder.

New study to find role of stress in development of dementia and Alzheimer’s disease

Stress link to Alzheimer’s goes under the spotlight — A new ?1.5 million study to find role of stress in development of dementia and Alzheimer’s disease – Chronic stress is being investigated in a new Alzheimer’s Society funded research project as a risk factor for developing dementia. It is part of a ?1.5 million package of six grants being given by the charity fighting to find a cause, cure and way to prevent the disease.

Alzheimer’s Disease patients may not get benefit from antioxidants

Alzheimer’s Disease patients may not get benefit from antioxidants

Clinical trial examines antioxidant effects for Alzheimer’s disease on cerebrospinal fluid biomarkers – An antioxidant combination of vitamin E, vitamin C and a-lipoic acid (E/C/ALA) was not associated with changes in some cerebrospinal fluid biomarkers related to Alzheimer disease in a randomized controlled trial, revealed by researchers.

Reversing Alzheimer’s gene blockade can restore memory

Reversing Alzheimer’s gene ‘blockade’ can restore memory, other cognitive functions — Neuroscientists show that HDAC2 enzyme could be a good target for new drugs – MIT neuroscientists have shown that an enzyme overproduced in the brains of Alzheimer’s patients creates a blockade that shuts off genes necessary to form new memories. Furthermore, by inhibiting that enzyme in mice, the researchers were able to reverse Alzheimer’s symptoms.

Bexarotene cancer drug may reverse Alzheimer’s symptoms

Drug quickly reverses Alzheimer’s symptoms in mice — Case Western Reserve researchers discover FDA-approved drug rapidly clears amyloid from the brain and reverses cognitive defects – Neuroscientists at Case Western Reserve University School of Medicine have made a dramatic breakthrough in their efforts to find a cure for Alzheimer’s disease. The research shows that use of a drug in mice appears to quickly reverse the pathological, cognitive and memory deficits caused by the onset of Alzheimer’s.

Brain stimulating habits lowers Alzheimer’s disease risk

Lifelong brain-stimulating habits linked to lower Alzheimer’s protein levels – Individuals who keep their brains active throughout life with cognitively stimulating activities such as reading, writing and playing games appear to have reduced levels of the ?-amyloid protein, which is the major part of the amyloid plaque in Alzheimer disease.

People with early Alzheimer’s disease may have lower BMI

People with early Alzheimer’s disease may be more likely to have lower BMI – People in the earliest stages of Alzheimer’s disease are more likely to have a lower body mass index (BMI). A new study examined 506 people with advanced brain imaging techniques and analyses of cerebrospinal fluid to look for biomarkers for Alzheimer’s disease, which can be present years before the first symptoms begin.

Blood test may detect Alzheimer’s Disease progression

Blood Tests May Hold Clues to Pace of Alzheimer?s Disease Progression – Researchers found a way to predict how quickly patients with Alzheimer’s disease (AD) will lose cognitive function by looking at ratios of two fatty compounds in their blood.

Diabetes increases risk of dementia and Alzheimer’s disease

Diabetes may significantly increase your risk of dementia and Alzheimer’s disease – People with diabetes appear to be at a significantly increased risk of developing dementia, revealed by researchers in a recent study published in Neurology, the medical journal of the American Academy of Neurology.