Stem cell transplants can cure Crohn’s disease patients
A clinical trial has begun which will use stem cell transplants to grow a new immune system for people with untreatable Crohn’s disease – a
Chemotherapy
Chemotherapy is treatment of cancer with anticancer drugs. Chemotherapy is administered in different ways, depending on the drugs to be given and the type of cancer. Doctors decide the dose of chemotherapy drugs considering many factors, among them being the patient’s height and weight.
Provenge – Sipuleucel-T may have added benefit in prostate cancer
Sipuleucel-T in prostate cancer: Indication of added benefit – Sipuleucel-T (trade name Provenge) has been approved since September 2014 for men with metastatic prostate cancer who have few or no symptoms and do not yet require chemotherapy. In the dossier assessment conducted by the German Institute for Quality and Efficiency in Health Care (IQWiG) in January 2015, no added benefit could be derived for sipuleucel-T.
Biomarker predicts effectiveness of brain cancer temozolomide treatment
Biomarker predicts effectiveness of brain cancer treatment – Researchers at the University of California, San Diego School of Medicine have identified a new biomarker that predicts whether glioblastoma – the most common form of primary brain cancer – will respond to chemotherapy.
ADT with docetaxel extends survival in metastatic prostate cancer
Drug Combination Extends Survival by More Than a Year in Metastatic Prostate Cancer – Men with newly diagnosed metastatic, hormone-sensitive prostate cancer lived more than a year longer when they received a chemotherapy drug docetaxel as initial treatment instead of waiting to for the disease to become resistant to hormone-blockers.
Mammography screening for breast cancer needs individualized approach
The mammography dilemma — Complex benefits and harms of mammography require individualized approach – A comprehensive review of 50 year’s worth of international studies assessing the benefits and harms of mammography screening suggests that the benefits of the screening are often overestimated, while harms are underestimated.
Blood stem cells longevity mechanism discovered
Mechanism Behind Blood Stem Cells’ Longevity Discovered – The blood stem cells that live in bone marrow are at the top of a complex family tree. Such stem cells split and divide down various pathways that ultimately produce red cells, white cells and platelets. These “daughter” cells must be produced at a rate of about one million per second to constantly replenish the body’s blood supply.
Prostate cancer – A change in circulating tumor cells detection has high potential in the prediction
Prostate cancer: A change in circulating tumor cells detection has high potential in the prediction – A new study reveals that in the prediction of treatment outcome for castration-resistant prostate cancer, a change in circulating tumour cells detection might be more accurate than the change in prostate-specific antigen levels.
Pazopanib better than sunitinib in advanced kidney cancer
Pazopanib shows better quality-of-life in advanced kidney cancer – Two oral targeted drugs — Pazopanib (Votrient) and sunitinib (Sutent) — approved for metastatic kidney cancer worked equally well, but one proved superior in tolerability, the safety profile and many measures of quality of life favored pazopanib.
Nanodiamonds may improve effectiveness of breast cancer treatment
UCLA researchers find nanodiamonds could improve effectiveness of breast cancer treatment – Recently, doctors have begun to categorize breast cancers into four main groups according to the genetic makeup of the cancer cells. Which category a cancer falls into generally determines the best method of treatment.
Kadcyla – new treatment for late stage HER2 breast cancer
US FDA approves new treatment for late-stage breast cancer – Kadcyla (ado-trastuzumab emtansine) – a new therapy for patients with HER2-positive, late-stage (metastatic) breast cancer is approved by US FDA. Breast cancer is the second leading cause of cancer-related death among women. Almost 20 percent of breast cancers have increased amounts of the HER2 protein.
Zaltrap for metastatic colorectal cancer approved by FDA
FDA approves Zaltrap for metastatic colorectal cancer – The U.S. Food and Drug Administration approved Zaltrap (ziv-aflibercept) for use in combination with a FOLFIRI (folinic acid, fluorouracil and irinotecan) chemotherapy regimen to treat adults with colorectal cancer.
Chemotherapy resistance develops due to WNT in cancer patients
Researchers discover new mechanism behind resistance to cancer treatment — Finding could lead to development of better therapies to cure cancer – Developing resistance to chemotherapy is a nearly universal, ultimately lethal consequence for cancer patients with solid tumors ? such as those of the breast, prostate, lung and colon ? that have metastasized, or spread, throughout the body.