Researchers at The University of Texas MD Anderson Cancer Center have made significant progress in treating leptomeningeal disease (LMD) caused by metastatic melanoma. LMD is a complication of cancer where cancer cells from primary tumors spread into the cerebrospinal fluid (CSF) and leptomeninges, the outer lining of the brain and spinal cord.
Renowned actor Sam Neill has disclosed his battle with an intensely aggressive form of non-Hodgkin lymphoma. The 75-year-old Jurassic Park icon was diagnosed with Stage three cancer in March 2022, believing, “I’m sick, I’m dying.” Unable to pursue acting, Neill turned to writing as a way to pass time and “provide a reason to get through the day,” he shared with the BBC.
Sipuleucel-T in prostate cancer: Indication of added benefit – Sipuleucel-T (trade name Provenge) has been approved since September 2014 for men with metastatic prostate cancer who have few or no symptoms and do not yet require chemotherapy. In the dossier assessment conducted by the German Institute for Quality and Efficiency in Health Care (IQWiG) in January 2015, no added benefit could be derived for sipuleucel-T.
Biomarker predicts effectiveness of brain cancer treatment – Researchers at the University of California, San Diego School of Medicine have identified a new biomarker that predicts whether glioblastoma – the most common form of primary brain cancer – will respond to chemotherapy.
Drug Combination Extends Survival by More Than a Year in Metastatic Prostate Cancer – Men with newly diagnosed metastatic, hormone-sensitive prostate cancer lived more than a year longer when they received a chemotherapy drug docetaxel as initial treatment instead of waiting to for the disease to become resistant to hormone-blockers.
The mammography dilemma — Complex benefits and harms of mammography require individualized approach – A comprehensive review of 50 year’s worth of international studies assessing the benefits and harms of mammography screening suggests that the benefits of the screening are often overestimated, while harms are underestimated.
Mechanism Behind Blood Stem Cells’ Longevity Discovered – The blood stem cells that live in bone marrow are at the top of a complex family tree. Such stem cells split and divide down various pathways that ultimately produce red cells, white cells and platelets. These “daughter” cells must be produced at a rate of about one million per second to constantly replenish the body’s blood supply.