For the first time, researchers have corrected a disease-causing mutation in early stage human embryos with gene editing. The technique, which uses the CRISPR-Cas9 system, corrected the mutation for a heart condition at the earliest stage of embryonic development so that the defect would not be passed on to future generations. With advances in stem … Read more
Study identifies 53 approved drugs that may block Ebola infection — Compounds may keep virus from entering cells; may accelerate drug development – Researchers found 53 existing drugs that may keep the Ebola virus from entering human cells, a key step in the process of infection. Among the better known drug types shown to hinder infection by an Ebola virus model: several cancer drugs, antihistamines and antibiotics.
Changes in scores of genes contribute to autism risk — Newfound genetic differences provide many hints at causes – Small differences in as many as a thousand genes contribute to risk for autism or autism spectrum disorder (ASD). This new study examined data on several types of rare, genetic differences in more than 14,000 DNA samples from parents, affected children, and unrelated individuals.
Low birth weight linked to higher incidence of type 2 diabetes in African American women – African American women born at a low or very low birth weight may be at a higher risk for developing type 2 diabetes.
Researchers develop first minimally invasive gene therapy procedure to treat heart rhythm disorders by transforming ordinary heart muscle cells into specialized rhythm-keeping cells, potentially eliminating future need for electronic pacemakers – Cardiologists at the Cedars-Sinai Heart Institute have developed a minimally invasive gene transplant procedure that changes unspecialized heart cells into “biological pacemaker” cells that keep the heart steadily beating.
New test predicts the risk of non-hereditary breast cancer — A simple blood test is currently in development that could help predict the likelihood of a woman developing breast cancer – A simple blood test is currently in development that could help predict the likelihood of a woman developing breast cancer, even in the absence of a high-risk BRCA1 gene mutation. This new research is published in the Genome Medicine.
Chinese herbal remedy as good as methotrexate for treating rheumatoid arthritis — And combination of Tripterygium wilfordii Hook F plus methotrexate even better – A traditional Chinese herbal remedy used to relieve joint pain and inflammation works as well as methotrexate, a standard drug treatment that is frequently prescribed to control the symptoms of active rheumatoid arthritis, reveals researchers.
How a versatile gut bacterium helps us get our daily dietary fiber – A common gut bacterium – Bacteroides ovatus – helps us metabolize a main component of dietary fibre xyloglucan from the cell walls of fruits and vegetables, revealed by researchers from University of British Columbia in the journal Nature.
Research backs risk-reduction surgery for ovarian cancer – Scientists back preventative surgery to improve survival for women who are at greater risk of getting ovarian cancer and suggest it appears helpful for women at risk of getting breast cancer because of genetic faults.
Smoking changes our genes – The fact that smoking means a considerable health risk is nowadays commonly accepted. New research findings from Uppsala University and Uppsala Clinical Research Center show that smoking alters several genes that can be associated with health problems for smokers, such as increased risk for cancer and diabetes.