New safety recommendations for high dose 80 mg simvastatin
FDA announces new safety recommendations for high-dose simvastatin — Increased risk of muscle injury cited – Patients taking simvastatin 80 mg daily had an increased risk of muscle injury. The risk of muscle injury is highest during the first year of treatment with the 80 mg dose of simvastatin, and is frequently associated with a genetic predisposition for simvastatin-related muscle injury or myopathy.