Gene-silencing study finds new targets for Parkinson’s disease — NIH study sheds light on treatment of related disorders – Scientists at the National Institutes of Health have used RNA interference (RNAi) technology to reveal dozens of genes which may represent new therapeutic targets for treating Parkinson’s disease. The findings also may be relevant to several diseases caused by damage to mitochondria, the biological power plants found in cells throughout the body.
Comprehensive Parkinson’s Biomarker Test Has Prognostic and Diagnostic Value, Penn Medicine Team Reports — First Biomarker Results from Parkinson’s Progression Markers Initiative Detect Differences in Subtypes of Parkinson’s Disease – The first biomarker results reported from the Parkinson’s Progression Markers Initiative (PPMI), showing that a comprehensive test of protein biomarkers in spinal fluid have prognostic and diagnostic value in early stages of Parkinson’s disease.
Pesticide exposure linked to Parkinson’s disease — Pesticide Exposure Tied to PD Risk – Exposure to pesticides, weed killers and solvents is likely to be associated with a higher risk for developing Parkinson’s disease, revealed by researchers in the Neurology, the medical journal of the American Academy of Neurology.
Statin Use Appears Associated with Modest Reduction in Parkinson Disease Risk – Regular use of cholesterol-lowering statin drugs may be associated with a modest reduction in risk for developing Parkinson disease, particularly among younger patients. Statins are one of the most prescribed classes of drugs in the United States.
Parkinson’s disease: Study of live human neurons reveals the disease’s genetic origins — UB researchers identify how the parkin gene works and how mutations cause Parkinson’s disease – Parkinson’s disease researchers at the University at Buffalo have discovered how mutations in the parkin gene cause the disease, which afflicts at least 500,000 Americans and for which there is no cure. The results are published in the current issue of Nature Communications.
Cognitive Decline in Patients with Parkinson Disease Associated With Certain Patterns of Brain Volume Decreases – Patients with Parkinson disease-related dementia appear to have increased brain atrophy in the hippocampal, temporal and parietal lobes and decreased prefrontal cortex volume compared to patients with Parkinson disease without dementia.
Lithium profoundly prevents brain damage associated with Parkinson’s disease — Buck Institute research in mice moves into preclinical stage; working toward human trials – Researcher are focusing on lithium as a potential treatment for Parkinson’s disease — PD — as well as its efficacy in combination with drugs currently used to control the symptoms of the disease. Lithium profoundly prevents the aggregation of toxic proteins and cell loss associated with Parkinson’s disease (PD) in a mouse model of the condition.
Parkinson’s patients sing in tune with creative arts therapy – Twice a month a jam session takes place on the third floor of Northwestern Memorial’s Prentice Women’s Hospital. A diverse group of men and women, ranging in age and ethnicity, gather in a circle with instruments in hand and sing together. This is no ordinary jam band; all its members have Parkinson’s disease. They are participating in Creative Arts for Parkinson’s, a music and drama therapy program offered through Northwestern’s Parkinson’s Disease and Movement Disorders Center.
High risk of Parkinson’s disease for people exposed to pesticides near workplace — Study first to implicate pesticide ziram as possible cause for disease – In April 2009, researchers at UCLA announced they had discovered a link between Parkinson’s disease and two chemicals commonly sprayed on crops to fight pests. That epidemiological study didn’t examine farmers who constantly work with pesticides but people who simply lived near where farm fields were sprayed with the fungicide maneb and the herbicide paraquat.
Eating berries may lower risk of Parkinson’s – New research shows men and women who regularly eat berries may have a lower risk of developing Parkinson’s disease, while men may also further lower their risk by regularly eating apples, oranges and other sources rich in dietary components called flavonoids.