Lung cancer cells’ survival gene 14-3-3zeta seen as drug target

Lung cancer cells’ survival gene 14-3-3zeta seen as drug target, as lung cancer cells can?t survive on their own when this key gene called 14-3-3zeta is silenced. – One of the deadliest forms of cancer appears to carry a specific weakness. When a key gene called 14-3-3zeta is silenced, lung cancer cells can’t survive on their own, researchers have found.

Mouth rinse gargle test for cancer

A simple mouth rinse may provide a new way to screen for head and neck cancers in people at high risk for these diseases. – A morning gargle could someday be more than a breath freshener ? it could spot head and neck cancer, say scientists at the Johns Hopkins Kimmel Cancer Center. Their new study of a mouth rinse that captures genetic signatures common to the disease holds promise for screening those at high risk, including heavy smokers and alcohol drinkers.

New screening strategy for detection of chagas disease

A new screening strategy could make it easier to diagnose and treat Chagas disease caused by a single cell parasite Trypanosoma cruzi, according to a US study. – A new targeted screening strategy could make the diagnosis and treatment of Chagas disease more feasible in low-resource settings, concludes a new study, publishing on December 26, 2007, in the open-access journal PLoS Neglected Tropical Diseases.

Colon cancer screenings could pose harm to some

R. Scott Braithwaite, M.D., and his colleagues developed a new method of evaluating medical screening tests like colonoscopy, called the “payoff time,” which is the minimum amount of time it takes for the benefits from a test to exceed its harms (i.e., its complications and side effects).
– Even though current guidelines advocate colorectal cancer screenings for those with severe illnesses, they may bring little benefit and may actually pose harm, according to a recent study by Yale School of Medicine researchers published in the Archives of Internal Medicine.

Predicting hip fracture risk in postmenopausal women

A team of UC Davis researchers has developed a method that assesses nearly a dozen factors to predict the five-year risk of hip fractures in postmenopausal women.
– To help doctors predict the five-year risk of hip fractures in their postmenopausal patients, a team of UC Davis researchers has developed a method that assesses nearly a dozen factors, including age, ethnicity and level of physical activity.

Obesity may be bad for bone health

Obesity and being over-weight may be bad for bone health, and childhood obesity could have a significant, long lasting negative impact on the skeleton. – Obesity may be bad for bone health, revealed by researchers at the University of Georgia. Being overweight is a known risk factor for heart disease, diabetes and a host of other health conditions. Now, obesity and over-weight may also be bad for bone health.

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