Genetic changes may lead to Barrett’s esophagus and esophageal cancer
Research discovers genetic link to Barrett’s esophagus, esophageal cancer — 5-year study identifies genes that predispose for BE/EAC – Mutations in three genes have been identified that are more prevalent in patients with esophageal cancer and Barrett esophagus, a premalignant metaplasia (change in cells or tissue) caused by chronic gastroesophageal reflux disease (GERD), according to preliminary research reported in the July 27 issue of JAMA.