Alzheimer's Disease Archives

MRI shows brain atrophy pattern that predicts Alzheimer’s Disease

Using special MRI methods, researchers have identified a pattern of regional brain atrophy in patients with mild cognitive impairment (MCI) that indicates a greater likelihood of progression to Alzheimer’s disease. – Researchers have identified a pattern of regional brain atrophy in patients with mild cognitive impairment (MCI) that indicates a greater likelihood of progression to Alzheimer’s disease. Researchers used special MRI methods.

Mediterranean diet improves cognitive impairment in Alzheimer’s disease

Higher adherence to the Mediterranean diet (MeDi) may protect from Alzheimer disease (AD). Its association with mild cognitive impairment (MCI) has been explored and proved in this study. – Eating a Mediterranean diet appears to be associated with less risk of mild cognitive impairment-a stage between normal aging and dementia-or of transitioning from mild cognitive impairment into Alzheimer’s disease.

Insulin may slow or prevent Alzheimer’s disease

Insulin is a possible new treatment for Alzheimer’s disease. Insulin may slow or prevent Alzheimer’s disease. – Insulin, by shielding memory-forming synapses from harm, may slow or prevent the damage and memory loss caused by toxic proteins in Alzheimer’s disease, reported by researchers at Northwestern University.

Retired athletes with mental decline after concussion

Brain function decline in healthy retired athletes who sustained their last sports concussion in early adulthood – Researchers have found the first evidence that athletes who were concussed during their earlier sporting life show a decline in their mental and physical processes more than 30 years later.

Dementia not in socially active old people

Socially active and not easily stressed? You may not develop dementia – A new study shows that people who are socially active and not easily stressed may be less likely to develop dementia.

NICE’s decision on Alzheimer’s drugs based on flawed calculations

Alzheimer’s drugs decision based on flawed calculations – Thousands of people with early stage Alzheimer’s are being denied access to the only drugs for the disease due to fundamental flaws in the way their cost effectiveness has been calculated.

Leptin sensitizing agents may help to lose weight

Obesity: Reviving the promise of leptin; The first known leptin-sensitizing agents induce mice to lose weight. – The discovery more than a decade ago of leptin, an appetite-suppressing hormone secreted by fat tissue, generated headlines and great hopes for an effective treatment for obesity. But hopes dimmed when it was found that obese people are unresponsive to leptin due to development of leptin resistance in the brain. Now, researchers at Children’s Hospital Boston report the first agents demonstrated to sensitize the brain to leptin: oral drugs that are already FDA-approved and known to be safe. Findings were published January 7 by the journal Cell Metabolism.

Diabetes slows mental functioning in adults

Adult-onset diabetes slows mental functioning in several ways, with deficits appearing early – Adults with diabetes experience a slowdown in several types of mental processing, which appears early in the disease and persists into old age, according to new research.

Blood sugar level linked to cognitive aging

Researchers at Columbia University Medical Center link blood sugar to normal cognitive aging – Maintaining blood sugar levels, even in the absence of disease, may be an important strategy for preserving cognitive health, suggests a study published by researchers at Columbia University Medical Center (CUMC).

Sleep disorder – an early sign of dementia, Parkinson’s disease

Sleep disorder may be early sign of dementia or Parkinson’s disease – People with a sleep disorder that causes them to kick or cry out during their sleep may be at greater risk of developing dementia or Parkinson’s disease, revealed by researchers.

Genetic disease recreated in lab

US researchers watched genetic diseases unfolding in the laboratory after finding a way to make large numbers of affected cells. – When neurons started dying in Clive Svendsen’s lab dishes, he couldn’t have been more pleased. The dying cells ? the same type lost in patients with the devastating neurological disease spinal muscular atrophy ? confirmed that the University of Wisconsin-Madison stem cell biologist had recreated the hallmarks of a genetic disorder in the lab, using stem cells derived from a patient.

Yeast to identify drugs for Alzheimer’s disease

Yeast could be used to develop a rapid screening process for identifying compounds which inhibit Alzheimer’s disease. – CSIRO scientists have developed a new system to screen for compounds that can inhibit one of the processes that takes place during the progression of Alzheimer’s disease.