Gene test identifies subtypes of breast cancer

Simple gene test identifies clinically important subtypes of breast cancer – A simple genetic test that uses just three genes is among the most effective means of classifying breast cancer into sub-types, US researchers report at the IMPAKT Breast Cancer Conference in Brussels, Belgium.

Sulforaphane in broccoli may limit breast cancer cells

Broccoli component limits breast cancer stem cells, U-M study finds — Research in mice, cells suggests possible prevention, treatment strategy – A compound derived from broccoli could help prevent or treat breast cancer by targeting cancer stem cells — the small number of cells that fuel a tumor’s growth — according to a new study from researchers at the University of Michigan Comprehensive Cancer Center.

Adolescent drinking adds to risk of breast disease breast cancer

Adolescent drinking adds to risk of breast disease, breast cancer – Girls and young women who drink alcohol increase their risk of benign (noncancerous) breast disease, says a study by researchers at Washington University School of Medicine in St. Louis and Harvard University.

BRCA mutation increases breast cancer risk in opposite breast

Breast cancer patients with BRCA mutations 4 times more likely to get cancer in opposite breast – Women with breast cancer before age 55 who carry an inherited mutation in the breast cancer susceptibility genes BRCA1 or BRCA2 are four times more likely to develop cancer in the breast opposite, or contralateral, to their initial tumor as compared to breast cancer patients without these genetic defects.

Isolated DNA Claims are Not Patentable, US

Federal District Court Rules Isolated DNA Claims are Not Patentable — Myriad to Appeal Decision to the Federal Circuit Court of Appeals – A federal judge on Monday struck down patents on two genes — BRCA1 and BRCA2 — linked to breast and ovarian cancer. Shares of Myriad Genetics (MYGN.O) fell as much as 7 percent, a day after the ruling.

Genomic sequencing of difficult breast cancers

Life Technologies, TGen and US Oncology partner on groundbreaking breast cancer sequencing research — First-of-its-kind project will sequence difficult breast cancers to provide insight into treatment strategies – Life Technologies Corporation (NASDAQ: LIFE) announced that it is collaborating with the Translational Genomics Research Institute (TGen) and US Oncology to sequence the genomes of 14 patients afflicted with triple negative breast cancer whose tumors have progressed despite multiple other therapies.

Radiotherapy delay increases breast cancer recurrence risk

Delaying post-surgical radiation increases risk of breast cancer recurrence in older women – Older women who have had breast cancer surgery have a greater risk of the cancer returning if they delay their post-surgical radiation treatment, report Dana-Farber Cancer Institute scientists.

New tool illuminates connections between stem cells and cancer

New tool illuminates connections between stem cells and cancer — 2010 Annual Meeting of the American Association for the Advancement of Science – Researchers have a new tool to understand how cancers grow — and with it a new opportunity to identify novel cancer drugs. They’ve been able to break apart human prostate tissue, extract the stem cells in that tissue, and alter those cells genetically so that they spur cancer.

Genetic link between breast density and breast cancer

Study reveals genetic link between mammographic density and breast cancer – A University of Melbourne study has revealed that certain breast cancer genetic variants increase mammographic density, confirming the link between mammographic breast density and breast cancer.

Few US women take tamoxifen to prevent breast cancer

Few women take tamoxifen to prevent breast cancer – Researchers with the National Cancer Institute (NCI) have found that the prevalence of tamoxifen use for the prevention of breast cancer among women without a personal history of breast cancer is very low.

Genes found linked to breast cancer drug resistance

Genes found linked to breast cancer drug resistance could guide future treatment choices – Researchers at Dana-Farber Cancer Institute have discovered a gene activity signature that predicts a high risk of cancer recurrence in certain breast tumors that have been treated with commonly used chemotherapy drugs.

Quitting smoking doubles survival in lung cancer patients

Lung cancer patients who quit smoking double their survival chances – People diagnosed with early stage lung cancer can double their chances of survival over five years if they stop smoking compared with those who continue to smoke.

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