Bexarotene cancer drug may reverse Alzheimer’s symptoms

Drug quickly reverses Alzheimer’s symptoms in mice — Case Western Reserve researchers discover FDA-approved drug rapidly clears amyloid from the brain and reverses cognitive defects – Neuroscientists at Case Western Reserve University School of Medicine have made a dramatic breakthrough in their efforts to find a cure for Alzheimer’s disease. The research shows that use of a drug in mice appears to quickly reverse the pathological, cognitive and memory deficits caused by the onset of Alzheimer’s.

Smoking linked to mental decline in men

Smoking associated with more rapid cognitive decline in men – Smoking in men appears to be associated with more rapid cognitive decline or mental decline. Smoking is increasingly recognized as a risk factor for dementia in the elderly and the number of dementia cases worldwide, estimated at 36 million in 2010, is on the rise and is projected to double every 20 years.

Cognitive decline linked to brain volume decreases in parkinson’s disease patients

Cognitive Decline in Patients with Parkinson Disease Associated With Certain Patterns of Brain Volume Decreases – Patients with Parkinson disease-related dementia appear to have increased brain atrophy in the hippocampal, temporal and parietal lobes and decreased prefrontal cortex volume compared to patients with Parkinson disease without dementia.

Medicare patients lead to long term institutionalization in a nursing home

Medicare patients at risk of long-term institutionalization after hospital stay — Discharge to skilled nursing facility a key factor, according to first national study – Confirming many elderly patients’ worst fears, a national study has shown that being hospitalized for an acute event, such as a stroke or hip fracture, can lead to long-term institutionalization in a nursing home.

Bipolar symptoms and emotional brain in youth

The emotional brain in youth – How to diagnose and treat bipolar symptoms and mood disorders in children and adolescents – Recognition of bipolar symptoms and bipolar disorder in adolescents is now clearly established. However, whether bipolarity exists in children remains controversial despite numerous studies that have been conducted on this topic in the last fifteen years.

Mild memory loss and thinking problems may impact life expectancy

Even mild cognitive impairment appears to substantially increase risk for death – Cognitive impairment, especially at the moderate to severe stages has an impact on life expectancy similar to chronic conditions such as diabetes or chronic heart failure, revealed by Regenstrief Institute and Indiana University researchers in a study “Cognitive Impairment: An Independent Predictor of Excess Mortality. A Cohort Study” published in Annals of Internal Medicine.

Allergan’s BOTOX will be available in European Countries for Urinary Incontinence

Allergan’s BOTOX? Receives A Positive Opinion in Fourteen European Countries for Urinary Incontinence in Patients with MS or Spinal Cord Injury – Allergan is pleased to announce that BOTOX (botulinum toxin type A) has received a positive opinion from the Irish Medicines Board for the management of urinary incontinence in adults with neurogenic detrusor overactivity (NDO) resulting from neurogenic bladder due to stable sub-cervical spinal cord injury, or multiple sclerosis.

People seek early diagnosis of Alzheimer’s disease

International survey highlights great public desire to seek early diagnosis of Alzheimer’s — Results from Europe and US highlight interest in early diagnosis despite wide fear of and familiarity with the condition – Results of an international survey reveal that over 85% of respondents in the five countries surveyed say that if they were exhibiting confusion and memory loss, they would want to see a doctor to determine if the cause of the symptoms was Alzheimer’s disease. Over 94% would want the same if a family member were exhibiting the symptoms.

Ovarian cancer screening does not improve survival

Ovarian cancer screening does not appear to reduce risk of ovarian cancer death – In a clinical trial that included nearly 80,000 women, those who received ovarian cancer screening did not have a reduced risk of death from ovarian cancer compared to women who received usual care, but did have an increase in invasive medical procedures and associated harms as a result of being screened.