Hypertension susceptibility gene STK39 identified

University of Maryland researchers identify common gene variant linked to high blood pressure. STK39 gene produces protein involved in regulating how kidneys process salt. – Researchers at the University of Maryland School of Medicine have identified a common gene variant that appears to influence people’s risk of developing high blood pressure, according to the results of a study being published online Dec. 29, 2008 in the Proceedings of the National Academy of Sciences (PNAS).

Brain genes linked to BMI, obesity

New research suggests that genes that predispose people to obesity act in the brain and that perhaps some people are simply hardwired to overeat. – A genetic study of more than 90,000 people has identified six new genetic variants that are associated with increased Body Mass Index (BMI), the most commonly used measure of obesity. Five of the genes are known to be active in the brain, suggesting that many genetic variants implicated in obesity might affect behaviour, rather than the chemical processes of energy or fat metabolism.

12 new genes identified for managing cholesterol, glucose, melatonin, sleep

New genes present drug targets for managing cholesterol and glucose levels – Scientists have identified 12 new genes that are somewhat strange bedfellows: Some link gallstones and blood cholesterol levels, others link melatonin and sleep patterns to small increases in glucose levels and larger jumps in the risk of diabetes.

A universal mechanism of aging is identified

New evidence may explain why it is that we lose not only our youthful looks, but also our youthful pattern of gene activity with age. – Researchers have discovered that DNA damage decreases a cell’s ability to regulate which genes are turned on and off in particular settings. This mechanism, which applies both to fungus and to us, might represent a universal culprit for aging.

New genes identified linked to lung cancer

Scientists find new genes linked to lung cancer. Discovery opens door to individualized treatment strategies. – Working as part of a multi-institutional collaboration, scientists at Washington University School of Medicine in St. Louis have assembled the most complete catalog to date of the genetic changes underlying the most common form of lung cancer.

23andMe announces breast cancer initiative

23andMe – Personal Genetics Leader to Focus on Building DNA-based Community For Women Impacted by Breast Cancer. – 23andMe, Inc., the industry leader in personal genetics, announced that it is embarking on a world-wide effort to assemble the largest cohort of women whose lives have been impacted by breast cancer and to build an infrastructure, based on genetics, that will accelerate consumer-based research of the disease.

New genes linked to gout

Three genes are associated with increased risk of higher levels of uric acid in the blood, which can lead to gout. – Researchers have identified two new genes ? and confirmed the role of a third gene ? associated with increased risk of higher levels of uric acid in the blood, which can lead to gout, a common, painful form of arthritis.

Gene found responsible for smoking habit

If your first cigarette gave you a buzz and you now smoke, a gene may be to blame; Link between initial smoking pleasure, lifetime smoking habits and variation in nicotine receptor gene found by U-M-led team. – Anyone who has ever tried smoking probably remembers that first cigarette vividly. For some, it brought a wave of nausea or a nasty coughing fit. For others, those first puffs also came with a rush of pleasure or “buzz.”

Chromosomal changes increase schizophrenia risk

Schizophrenia may be partly caused by the effects of unusual structural changes in genes. – People with schizophrenia (mental illness variously affecting behavior, thinking, and emotion) have an increased number of unusual chromosomal changes, particularly structural changes that have the potential to alter the function of the genes.

New melanoma gene close to be identified

Results published today from a study led by researchers from The Translational Genomic Research Institute (TGen) in Phoenix, Arizona and The Queensland Institute of Medical Research (QIMR), Queensland, Australia, however, may yet change these statistics. The team is close to discovering a new gene that could help explain variation in melanoma risk. – The researchers are close to discovering a new gene that could help explain variation in melanoma risk. They have identified a region on chromosome 20 (20q11.22) that influences a person’s risk of developing melanoma.

Health Newstrack