Heart failure is a condition in which the heart has lost the ability to pump enough blood to the body’s tissues. With too little blood being delivered, the organs and other tissues do not receive enough oxygen and nutrients to function properly.
Disrupting an antioxidant pathway prevents heart disease caused by reductive stress – Researchers have found that deficiency of an antioxidant response protein called nuclear erythroid-2 like factor-2 (Nrf2) delays or prevents hypertrophic cardiomyopathy, a type of a heart failure in which the heart muscle grows abnormally thick.
UCLA researchers find nanodiamonds could improve effectiveness of breast cancer treatment – Recently, doctors have begun to categorize breast cancers into four main groups according to the genetic makeup of the cancer cells. Which category a cancer falls into generally determines the best method of treatment.
Cleveland Clinic research shows anemia drug does not improve health of anemic heart failure patients — Phase 3 findings published in NEJM provide answers about treatment with darbepoetin alfa – Researchers from Cleveland Clinic and Sweden-based Sahlgrenska University Hospital have found that a commonly used drug to treat anemia in heart failure patients – darbepoetin alfa – does not improve patients’ health, nor does it reduce their risk of death from heart failure.
Pacemaker could help more heart failure patients – A new study from Karolinska Institutet demonstrates that a change in the ECG wave called the QRS prolongation is associated with a higher rate of heart-failure mortality. According to the team that carried out the study suggests that more heart failure cases could be helped by pacemakers.
Popular antidepressant might prevent heart failure – A medication usually used to help treat depression and anxiety disorders has the potential to help prevent heart failure. John Tesmer, research professor at the U-M Life Sciences Institute and professor in the Department of Pharmacology at the U-M Medical School, and his research team at the Tesmer lab found that paroxetine, a selective serotonin reuptake inhibitor (SSRI) sold under the name Paxil, inhibits G protein-coupled receptor kinase 2 (GRK2), a protein kinase that becomes over-expressed when people have heart failure.
Midlife fitness staves off chronic disease at end of life, UT Southwestern researchers report — Fitness at 50 – free from chronic illness – Being physically fit during your 30s, 40s, and 50s not only helps extend lifespan, but it also increases the chances of aging healthily, free from chronic illness. For decades, research has shown that higher cardiorespiratory fitness levels lessen the risk of death, but it previously had been unknown just how much fitness might affect the burden of chronic disease in the most senior years ? a concept known as morbidity compression.
Exercise boosts mental and physical health of heart failure patients — Exercise results in modest reduction in depressive symptoms for patients with chronic heart failure – Moderate exercise helps ease depression in patients with chronic heart failure, and is also associated with a small but significant reduction in deaths and hospitalizations.
Regular, moderate, coffee drinking may reduce heart failure risk — Yes, moderate coffee consumption offers protection against heart failure – If you drink coffee regularly in moderation, you could reduce your risk of heart failure. Researchers, analyzing previous studies on the link between coffee consumption and heart failure, found that moderate coffee drinking as part of a daily routine may be linked with a significantly lower risk of heart failure. In contrast, indulging excessively may be linked with an increased chance of developing serious heart problems.
Studies examine CPAP treatment and cardiovascular outcomes in adults with obstructive sleep apnea — Treatment of Obstructed Sleep Apnea With CPAP Therapy Associated With A Lower Risk Of Hypertension – Two studies that included adults with obstructive sleep apnea examined the effectiveness of reducing the risk of cardiovascular outcomes, including high blood pressure, by treatment with continuous positive airway pressure (CPAP).
Risk of stroke greater for women than men among older patients diagnosed with atrial fibrillation – In a study that examined use of the anticoagulant medication warfarin and risk of stroke following a diagnosis of atrial fibrillation in older patients, women, especially those 75 years or older, had a higher risk of stroke than men, regardless of their risk profile and use of warfarin, suggesting that current anticoagulant therapy to prevent stroke might not be sufficient for older women.
