International AIDS Society updates treatment guidelines for HIV infection

The availability of new antiretroviral drugs and formulations, including drugs in new classes, and recent data on treatment choices for antiretroviral-naive and -experienced patients warrant an update of the International AIDS Society?USA guidelines for the use of antiretroviral therapy in adult human immunodeficiency virus (HIV) infection. – An evaluation of recent data has led to an update in the guidelines and recommendations for antiretroviral treatment of adult human immunodeficiency virus (HIV) infection, according to an article in the August 6 issue of JAMA, a theme issue on HIV/AIDS.

40% higher HIV infection estimate in US

HIV Medicine Association (HIVMA) reported that higher HIV infection estimate in US shows need for routine screening, more funding for care. – The Centers for Disease Control and Prevention (CDC) is expected soon to increase the estimate of new HIV infections in the United States by 40 percent. This highlights the need to make HIV testing a routine part of medical care and provide better funding to care for those who test positive, according to the HIV Medicine Association (HIVMA).

Genetic variation in Africans raises HIV risk

A variant of a gene found only in people of African ancestry increases the odds of becoming infected with the human immunodeficiency virus (HIV-1) by 40 percent. – A genetic variation which evolved to protect people of African descent against malaria has now been shown to increase their susceptibility to HIV infection by up to 40 per cent, according to new research. Conversely, the same variation also appears to prolong survival of those infected with HIV by approximately two years.

Oestrogen makes male organ resistant to HIV

A new avenue to possibly prevent HIV infection of the penis – topical estrogen to the human penis increased the thickness of the natural keratin layer on the skin, which could prevent HIV from infecting the male. – Topical oestrogen applied to the human penis could stop the spread of HIV, revealed by Australian researchers at the University of Melbourne.

OPAL Therapy cost-effective method of treating HIV

New ‘OPAL Therapy’ presents simple, cost-effective method of treating HIV infection – Australian researchers have unveiled a new immunotherapy technique to help prevent the progression from HIV infection to AIDS. Details of the simple, cost-effective technique are published May 2nd in the open-access journal PLoS Pathogens.

Monitoring AIDS treatment by physical signs is effective

When clinicians use simple physical signs of deteriorating health — such as weight loss or fever — these doctors can provide therapies almost as effective as those relying on the most advanced laboratory analysis. – When millions of HIV-infected people in poor countries began receiving advanced drug therapies, critics worried that patient care would suffer because few high-tech laboratories were available to guide treatments. But according to a study being published in The Lancet, these concerns are as yet unfounded.

CD16 monocyte could be a biomarker for progression of HIV

Expansion of a monocyte subset in HIV patients could serve as a biomarker for progression of the disease. – An increase in the CD163+/CD16+ monocyte subset could be a biomarker for the progression of HIV disease, according to researchers at Temple University, reported in the March issue of AIDS Research and Human Retroviruses.

HIV cases reduced in New Zealand

New Zealand AIDS Foundation is welcoming the reduction in overall numbers of new HIV diagnoses in 2007, in particular that diagnoses among gay and bisexual men have remained equivalent to 2006 levels. – The New Zealand AIDS Foundation is welcoming the reduction in overall numbers of new HIV diagnoses in 2007, in particular that diagnoses among gay and bisexual men have remained equivalent to 2006 levels.

HIV AIDS organisations to highlight progress and lessons learned

HIV/AIDS implementers from around the world will gather in Kampala, Uganda, from June 3-7 for the 2008 HIV/AIDS Implementers? Meeting. – HIV/AIDS implementers from around the world will gather in Kampala, Uganda, from June 3-7 for the 2008 HIV/AIDS Implementers’ Meeting. Recognizing the rapid expansion of HIV/AIDS programs worldwide, the focus of this year’s meeting is building the capacity of local prevention, treatment, and care programs; enhancing quality; and promoting coordination among partners.

Researchers discover TRIM22 gene that blocks HIV

Canadian researchers at the University of Alberta have discovered a gene that can block HIV, and in turn prevent the onset of AIDS. – Researchers at the University of Alberta have discovered a gene that is able to block HIV, and in turn prevent the onset of AIDS. Stephen Barr, a molecular virologist in the Department of Medical Microbiology and Immunology, says his team has identified a gene called TRIM22 that can block HIV infection in a cell culture by preventing the assembly of the virus.

Tenofovir gel safe for daily use

Trial finds tenofovir gel safe for daily use and most women adhered to study regimens; Results of Phase II study of ARV-based microbicide presented at international meeting in India bolster interest in latest approach – A vag inal microbicide that incorporates an antiretroviral (ARV) drug normally used to treat people with HIV is safe for sexually active HIV-negative women to use every day over an extended period, suggest results of a clinical trial of tenofovir topical gel.

Anti HIV gel Tenofovir proven safe for women

A gel using anti-HIV drug tenofovir to shield women from AIDS has been proven safe for daily use and acceptable to women. – An experimental anti HIV gel is safe for women to use on a daily basis, according to researchers at the University of Alabama at Birmingham (UAB) and the University of Pittsburgh School of Medicine.

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