Kidney Archives

Low birth weight may increase heart disease and kidney disease risk

Low birth weight may increase risk for cardiovascular disease, kidney disease and diabetes — New research in The FASEB Journal suggests that poor high blood pressure management during pregnancy may have negative long-term health consequences for offspring – Being underweight at birth may have consequences above and beyond the known short-term effects says a research report. The report shows that rats with a low birth weight have an increased long-term risk for developing cardiovascular disease, kidney disease, and diabetes.

Gene therapy may restore sense of smell

Can’t smell anything? This discovery may give you hope – Gene therapy in mice restores sense of smell, may also aid research into other diseases caused by cilia defects, U-M researchers say – Scientists have restored the sense of smell in mice through gene therapy for the first time — a hopeful sign for people who can’t smell anything from birth or lose it due to disease. The achievement in curing congenital anosmia — the medical term for lifelong inability to detect odors — may also aid research on other conditions that also stem from problems with the cilia.

Stribild once a day combination pill to treat HIV

FDA approves new combination pill for HIV treatment for some patients – Stribild (elvitegravir, cobicistat, emtricitabine, tenofovir disoproxil fumarate), a new once-a-day combination pill to treat HIV-1 infection in adults who have never been treated for HIV infection, is approved in US by FDA.

Truvada approved to reduce HIV infection risk in uninfected

FDA approves first drug for reducing the risk of sexually acquired HIV infection — Evidence-based approach enhances existing prevention strategies – The U.S. Food and Drug Administration has approved Truvada (emtricitabine/tenofovir disoproxil fumarate), the first drug approved to reduce the risk of HIV infection in uninfected individuals who are at high risk of HIV infection and who may engage in sexual activity with HIV-infected partners.

High blood pressure risk rising in US kids

More hospitalizations, higher charges, for kids with high blood pressure – Hospitalizations for children with high blood pressure and related charges dramatically increased during 10 years ending in 2006, according to a study published in the American Heart Association journal Hypertension. This nationally-based study is the first in which researchers examined hypertension hospitalizations in children.

Alcohol abuse increases after bariatric surgery

Adults who had a common bariatric surgery to lose weight had a significantly higher risk of alcohol use disorders (AUD) two years after surgery – Among patients who underwent bariatric surgery, there was a higher prevalence of alcohol use disorders in the second year after surgery, and specifically after Roux-en-Y gastric bypass, compared with the years immediately before and following surgery.

One kidney transplanted 2 times in 2 weeks

Kidney transplanted twice in 2 weeks — Transplant recipient donates kidney after disease threatens the organ; re-implantation reverses damage and allows another patient to thrive – For the first time, a kidney that had been donated to a patient in need was removed and implanted into a new patient, the third individual to have the organ, after it failed in the first transplant recipient.

Vitamin D therapy does not improve heart disease risk

Vitamin D Therapy Does Not Improve Certain Cardiac Measures for Patients With Chronic Kidney Disease – Patients with chronic kidney disease who received the vitamin D compound paricalcitol for up to 48 weeks did not show improvement on measures of cardiac structure, function, or left ventricular mass, compared to patients who received placebo.

Avastin bevacizumab approval revoked to treat breast cancer in US

Avastin Loses FDA Approval to Treat Breast Cancer – US health agency FDA Commissioner Margaret A. Hamburg, M.D. has revoked the approval of the breast cancer indication for Avastin (bevacizumab) after concluding that the drug has not been shown to be safe and effective for that use.

35 new drugs approved in 2011 in US

FDA: 35 innovative new drugs approved in fiscal year 2011 — Report shows quick approvals of safe and effective medicines occur in the United States before other countries – Over the past 12 months, the U.S. Food and Drug Administration approved 35 new medicines for patients, like two new treatments for hepatitis C; a drug for late-stage prostate cancer; the first new drug for Hodgkin’s lymphoma in 30 years; and the first new drug for lupus in 50 years.

Expandable prosthesis resolves advanced aortic valve disease

University Hospitals Case Medical Center physician-scientists participate in new multidisciplinary program and clinical trial – Among individuals 65 years and older, as many as 30 percent have aortic valve sclerosis or stenosis and as a result of their deteriorating health, they cannot enjoy a normal lifestyle.

Allergan’s BOTOX will be available in European Countries for Urinary Incontinence

Allergan’s BOTOX? Receives A Positive Opinion in Fourteen European Countries for Urinary Incontinence in Patients with MS or Spinal Cord Injury – Allergan is pleased to announce that BOTOX (botulinum toxin type A) has received a positive opinion from the Irish Medicines Board for the management of urinary incontinence in adults with neurogenic detrusor overactivity (NDO) resulting from neurogenic bladder due to stable sub-cervical spinal cord injury, or multiple sclerosis.