Test for targeted therapy in acute myeloid leukemia

Researchers have discovered that a particular hormone is responsible for driving a cancer enzyme to cause an often deadly red blood cell cancer, Polycythemia vera.
– An Oregon Health & Science University Cancer Institute researcher has discovered that a particular hormone is responsible for driving a cancer enzyme to cause an often deadly red blood cell cancer.

Gleevec improves special leukemia in children

Gleevec has been shown to improve outcomes for children with Philadelphia chromosome-positive acute lymphoblastic leukemia.
– Gleevec, the targeted cancer pill that has saved more than 100,000 lives, now is saving more children with a dire leukemia, as well as preventing disease progression with long term use in adults with chronic myeloid leukemia.

Understanding chronic myeloid leukemia

Researchers have discovered abnormal cells in the early stem cell population in Chronic myeloid leukemia CML patients.
– Oregon Health & Science University Cancer Institute researchers have opened a new window into the roots of chronic myeloid leukemia (CML). “We are looking under the surface of CML to understand better where the cancer is coming from. We have discovered abnormal cells in the early stem cell population in some CML patients, which don’t belong to the CML clone. These are abnormal cells that are not part of the CML clone,” said Thomas Bumm, M.D., OHSU Cancer Institute member.

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