HER growth proteins do not predict outcome of herceptin treatment breast cancer patients

Proteins do not predict outcome of herceptin treatment in HER2-positive breast cancer – Precisely quantifying the amount of three different HER growth proteins, along with several other proteins believed linked to breast cancer, did not predict a patient’s outcome after treatment for HER2 Positive Breast Cancer with Herceptin, say Mayo Clinic researchers.

PSA test helps predicting biopsy need and low risk prostate cancer

Mayo Clinic study: PSA test valuable in predicting biopsy need, low-risk prostate cancer – The prostate-specific antigen test, commonly known as the PSA test, is valuable in predicting which men should have biopsies and which are likely to be diagnosed with low-risk prostate cancer, a Mayo Clinic study has found. The findings were released during a meeting of the North Central Section of the American Urological Association in Rancho Mirage, California, US.

Children with multiple surgeries before age 2 develop a learning disability

Mayo Clinic study: multiple surgeries and anesthesia exposure – 36.6 percent children who had multiple surgeries before age 2 developed a learning disability later in life, but it should not alter decision-making related to surgery in young children. The new study examines children experiencing anesthesia and surgeries under age 2.

Advanced stage prostate cancer patients experience 20 year survival rates with surgery

Advanced-stage prostate cancer patients experience 20-year survival rates with surgery – Long-term survival rates for patients with advanced prostate cancer suggest they can be good candidates for surgery, Mayo Clinic researchers have found. Their study found a 20-year survival rate for 80 percent of patients diagnosed with cancer that has potentially spread beyond the prostate, known as cT3 prostate cancer, and treated with radical prostatectomy, or surgery to remove the prostate gland.

New GM-SCF therapy to defeating flu shows promise

New approach to defeating flu shows promise – New research on mice has shown that pulmonary administration of granulocyte macrophage-colony stimulating factor (GM-CSF) significantly reduces flu symptoms and prevents death after a lethal dose influenza virus.

Diabetes drug rosiglitazone linked to heart problems

New study adds weight to diabetes drug link to heart problems — Research: Comparative cardiovascular effects of thiazolidinediones: Systematic review and meta-analysis of observational studies – A new study published on bmj adds to mounting evidence that rosiglitazone – a drug used to treat type 2 diabetes – is associated with an increased risk of major heart problems.

New stool test to predict colon cancer

New test measures DNA methylation levels to predict colon cancer – An investigational DNA methylation test could alter the screening landscape for colorectal cancer, according to data presented at the American Association for Cancer Research special conference on Colorectal Cancer: Biology to Therapy, held here Oct. 27-30, 2010.

Rheumatoid arthritis incidence on the rise in women

Rheumatoid arthritis incidence on the rise in women — Study suggests environmental factors may be cause of increase – The incidence of rheumatoid arthritis (RA) in women has risen during the period of 1995 to 2007, according to a newly published study by researchers from the Mayo Clinic.

Exercise may prevent, improve cognitive impairment

Aerobic exercise has a better effect on cognition and other biomarkers associated with Alzheimer disease pathology for older adults with mild cognitive impairment. – Moderate physical activity performed in midlife or later appears to be associated with a reduced risk of mild cognitive impairment, whereas a six-month high-intensity aerobic exercise program may improve cognitive function in individuals who already have the condition.

Study provides insight into pathway linked to obesity

Mayo researchers collaborating with investigators at the University of Iowa, University of Connecticut and New York University (NYU) have discovered a molecular mechanism that controls energy expenditure in muscles and helps determine body weight. Researchers say this could lead to a new medical approach in treating obesity. – A new study involving the University of Iowa, Mayo Clinic and two other institutions provides insight on weight control, suggesting that a ATP-sensitive potassium channel critical to survival and stress adaptation can contribute to fat deposition and obesity.