Stem cell transplant may restore memory

Stem cell transplant restores memory, learning in mice – A study at the University of Wisconsin-Madison is the first to show that human stem cells can successfully implant themselves in the brain and then heal neurological deficits, says senior author Su-Chun Zhang, a professor of neuroscience and neurology.

Cholesterol increases Alzheimer’s disease and Heart disease risks

Cholesterol increases risk of Alzheimer’s and heart disease – High levels of blood cholesterol increase the risk of both Alzheimer’s disease and heart disease, but it has been unclear exactly how cholesterol damages the brain to promote Alzheimer’s disease and blood vessels to promote atherosclerosis.

Propranolol may improve working memory in autism patients

Drug could improve working memory of people with autism, study finds – People with an Autism Spectrum Disorder (ASD) often have trouble communicating and interacting with others because they process language, facial expressions and social cues differently. Previously, researchers found that propranolol, a drug commonly used to treat high blood pressure, anxiety and panic, could improve the language abilities and social functioning of people with an ASD. Now, University of Missouri investigators say the prescription drug also could help improve the working memory abilities of individuals with autism.

Athletes with suspected concussion should be removed from play – AAN US

American Academy of Neurology (AAN) Issues Updated Sports Concussion Guideline: Athletes with Suspected Concussion Should Be Removed from Play – With more than one million athletes now experiencing a concussion each year in the United States, the American Academy of Neurology (AAN) has released an evidence-based guideline for evaluating and managing athletes with concussion. This new guideline replaces the 1997 AAN guideline on the same topic.

Buphenyl a possible drug for Alzheimer’s disease

Rush scientists identify buphenyl as a possible drug for Alzheimer’s disease – Buphenyl, an FDA-approved medication for hyperammonemia, may protect memory and prevent the progression of Alzheimer’s disease. Hyperammonemia is a life-threatening condition that can affect patients at any age. It is caused by abnormal, high levels of ammonia in the blood.

Early detection of PML improves survival of multiple sclerosis patients

Early detection of MS treatment complication may improve survival – The drug natalizumab is effective for treating multiple sclerosis (MS), but it increases the risk of a rare but potentially fatal brain infection called progressive multifocal leukoencephalopathy (PML). The study suggests that early detection of PML may help improve survival and disability levels.

Blocked heart arteries can cause stroke

Clogged heart arteries can foreshadow stroke — American Heart Association Rapid Access Journal Report – Blockages in your heart arteries could mean you’re more likely to have a stroke, even if you’re considered low risk. A new study raises the need for intensified interdisciplinary efforts for providing adequate disease prevention and management strategies for stroke.

Delivery of drug tPA directly into brain helps stroke patients

Treatment with clot-busting drug yields better results after stroke than supportive therapy alone – In an update to previous research, Johns Hopkins neurologists say minimally invasive delivery of the drug tPA directly into potentially lethal blood clots in the brain helped more patients function independently a year after suffering an intracerebral hemorrhage (ICH), a deadly and debilitating form of stroke.

Multiple sclerosis – possible trigger for nerve damage

NIH-funded researchers show possible trigger for MS nerve damage — Results of study in mice may lead to new treatments – High-resolution real-time images show in mice how nerves may be damaged during the earliest stages of multiple sclerosis. The results suggest that the critical step happens when fibrinogen, a blood-clotting protein, leaks into the central nervous system and activates immune cells called microglia.

Stroke becoming more common in young people

Study: Stroke becoming more common in young people – Stroke may be affecting people at a younger age, revealed by researchers. “The reasons for this trend could be a rise in risk factors such as diabetes, obesity and high cholesterol,” said study author Brett Kissela, MD, MS, with the University of Cincinnati College of Medicine in Ohio and a Fellow of the American Academy of Neurology.

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