Pfizer new drug could provide a new treatment option for postmenopausal women

Pfizer new drug BZA/CE could provide a new treatment option for symptomatic postmenopausal women with a uterus – Pfizer Inc. will announce new one-year results from the Selective estrogens, Menopause, And Response to Therapy [SMART]-5 Phase 3 study of the safety and efficacy of the investigational tissue selective estrogen complex (TSEC) bazedoxifene/conjugated estrogens (BZA/CE) at the 22nd annual meeting of the North American Menopause Society (NAMS), September_21-24 in Washington, D.C.

Facial wrinkles may predict bone density in early menopause

Severity of facial wrinkles may predict bone density in early menopause – In postmenopausal women the appearance of the skin may offer a glimpse of the skeletal well-being, a relationship not previously described, said Lubna Pal, MD, a reproductive endocrinologist and associate professor at Yale School of Medicine, New Haven, Conn. The worse a woman’s skin wrinkles are during the first few years of menopause, the lower her bone density is.

Pfizer drug reduces breast cancer in high risk women

UB played major role in study on drug that reduces breast cancer in high-risk women — Buffalo enrolled more women than any other study site – The drug exemestane significantly reduces the risk of breast cancer in high-risk, postmenopausal women is the result of an international, randomized double-blind phase III clinical trial in which University at Buffalo researchers and hundreds of Western New York women played a critical role, revealed at the American Society of Clinical Oncology annual meeting.

Baked or broiled fish lowers heart failure risk

Heart failure risk lower in women who often eat baked/broiled fish – The risk of developing heart failure was lower for postmenopausal women who frequently ate baked or broiled fish, but higher for those who ate more fried fish, in a study reported in Circulation: Heart Failure, an American Heart Association journal.

Breast cancer survivors at higher risk for fractures

Breast cancer survivors at higher risk for falls — Cancer therapies may affect balance, according to new study in the Archives of Physical Medicine and Rehabilitation – The combined effects of chemotherapy and endocrine therapy may increase the risk of bone fractures in breast cancer survivors, revealed by researchers in a study.

Hormone therapy at menopause may lead to breast cancer

Hormone therapy begun at menopause may pose risk for breast cancer – Hormone therapy around menopause is linked to breast cancer risk, revealed by researchers in a study published in The Journal of the National Cancer Institute.

Antidepressant may reduce menopausal hot flashes

Use of Antidepressant Associated With Reduction in Menopausal Hot Flashes – Women who were either in the transition to menopause or postmenopausal experienced a reduction in the frequency and severity of menopausal hot flashes with the use of the antidepressant medication escitalopram, compared to women who received placebo.

Body fat distribution linked to ER negative breast cancer

Body fat distribution associated with a higher risk of ER-negative breast cancer – Body fat distribution does not play an important role in the incidence of every subtype of premenopausal breast cancer, but is associated with an increased risk for estrogen receptor (ER)?negative breast cancer.

Obesity in colon cancer patients increases mortality

Obesity or abnormal body weight related to increased mortality in colon cancer patients – Postmenopausal women diagnosed with colon cancer may be at increased risk of death if they fail to maintain a healthy body weight before cancer diagnosis, revealed by researchers.

Cancer risk found for long-term hormone therapy

Cancer risk found for long-term hormone therapy — USC researchers determine continued risks of breast cancer for women who use postmenopausal hormone therapy – Using postmenopausal hormone therapy for more than 15 years increases a woman’s risk of developing breast cancer, particularly among leaner women according to research at the Keck School of Medicine of the University of Southern California (USC).