Pregnancy risk Archives

Secondhand smoke affect cystic fibrosis lung disease

Any exposure to secondhand smoke adversely affects both cross-sectional and longitudinal measures of lung function in individuals with cystic fibrosis CF. Variations in the gene that causes CF (CFTR) and a CF-modifier gene (TGF?1) amplify the negative effects of secondhand smoke exposure. – Exposure to secondhand smoke is associated with adverse effects on lung function among persons with cystic fibrosis, with this effect being worse for persons with certain gene variations, according to a study in the January 30 issue of Journal of the American Medical Association (JAMA).

Caffeine during pregnancy increases miscarriage risk

If you are pregnant and need caffeine to get you going, try keeping it to one cup or less a day. Avoiding it may be even better. – High doses of daily caffeine during pregnancy ? whether from coffee, tea, caffeinated soda or hot chocolate ? cause an increased risk of miscarriage, according a new study by the Kaiser Permanente Division of Research. The study controlled, for the first time, pregnancy-related symptoms of nausea, vomiting and caffeine aversion that tended to interfere with the determination of caffeine’s true effect on miscarriage risk.

Intelence, etravirine HIV Drug approved in US

The U.S. Food and Drug Administration approved etravirine tablets for the treatment of HIV infection in adults who have failed treatment with other antiretrovirals. Etravirine is a non-nucleoside reverse transcriptase inhibitor (NNRTI) that helps to block an enzyme which HIV needs to multiply. – US FDA approved Tibotec Therapeutics’ Intelence, etravirine tablets for the treatment of HIV infection, to be used in combination with other anti-HIV medications, in adults who have failed treatment with other antiretrovirals.

Ortho Evra contraceptive transdermal birth control patch label update

Ortho Women?s Health & Urology, Division of Ortho-McNeil-Janssen Pharmaceuticals, Inc., has updated the prescribing information for ORTHO EVRA (norelgestromin/ethinyl estradiol transdermal system) to include further epidemiologic data. – The U.S. Food and Drug Administration (FDA) approved additional changes to the Ortho Evra Contraceptive Transdermal (Skin) Patch label to include the results of a new epidemiology study that found that users of the birth control patch were at higher risk of developing serious blood clots, also known as venous thromboembolism (VTE), than women using birth control pills. VTE can lead to pulmonary embolism.

Obese pregnant women give birth to heavier babies

New study suggests that maternal body composition at or near conception has important implications for offspring?s obesity, and obesity during conception phase may set the stage for offspring?s obesity risk. – The number of overweight and obese Americans continues to grow rapidly. Today, 50 percent of adults are overweight and up to 20 percent are obese. While the number of overweight/obese children is at an all time high, the steady increase of overweight infants ? individuals under 11 months old ? is alarming.