UCSB, UCL scientists rescue visual function in rats using induced pluripotent stem cells – An international team of scientists has rescued visual function in laboratory rats with eye disease by using cells similar to stem cells. The research shows the potential for stem cell-based therapies to treat age-related macular degeneration in humans.
New stem cell technology developed at Hebrew University — Leads to better treatment for complicated bone fractures – Researchers have developed a new way of using stem cells to provide better and rapid healing for patients suffering from complicated bone fractures.
First reconstitution of an epidermis from human embryonic stem cells – Stem cells to create new skin for patients with burns and skin diseases. – Researchers has succeeded in recreating a whole epidermis from human embryonic stem cells, revealed in a new study conducted by Marc Peschanski of INSERM published in the Lancet.
Stem cell therapy may offer hope for acute lung injury – Adult stem cells from bone marrow can prevent acute lung injury in a mouse model of the disease, revealed by researchers at the University of Illinois at Chicago College of Medicine.
What makes stem cells tick? — Researchers identify phosphorylated signaling proteins in human embryonic stem cells. – Investigators at the Burnham Institute for Medical Research (Burnham) and The Scripps Research Institute (TSRI) have made the first comparative, large-scale phosphoproteomic analysis of human embryonic stem cells (hESCs) and their differentiated derivatives.
Stem cells cultured on a simple contact lens to restore sight to sufferers of blinding corneal disease. – In a world-first breakthrough, University of New South Wales (UNSW) medical researchers have used stem cells cultured on a simple contact lens to restore sight to sufferers of blinding corneal disease.
LIN28, which maintains cell ‘stemness,’ is abundant in advanced cancers and transforms cells to cancerous state – A protein abundant in embryonic stem cells is now shown to be important in cancer, and offers a possible new target for drug development, report researchers from the Stem Cell Program at Children’s Hospital Boston.
Combined stem cell-gene therapy approach cures human genetic disease in vitro – A study led by researchers at the Salk Institute for Biological Studies, has catapulted the field of regenerative medicine significantly forward, proving in principle that a human genetic disease can be cured using a combination of gene therapy and induced pluripotent stem (iPS) cell technology.
Embryo’s heartbeat drives blood stem cell formation – Clues about how blood forms could yield new strategies for treating blood diseases. – Biologists have long wondered why the embryonic heart begins beating so early, before the tissues actually need to be infused with blood. Two groups of researchers from Children’s Hospital Boston, Brigham and Women’s Hospital, and the Harvard Stem Cell Institute (HSCI) -? presenting multiple lines of evidence from zebrafish, mice and mouse embryonic stem cells -? provide an intriguing answer: A beating heart and blood flow are necessary for development of the blood system, which relies on mechanical stresses to cue its formation.
A major breakthrough in generating safer, therapeutic stem cells from adult cells. – In a paper publishing online April 23rd in Cell Stem Cell, a Cell Press journal, Dr. Sheng Ding and colleagues from the Scripps Research Institute in La Jolla, California, report an important step forward in the race to make reprogrammed stem cells that may be better suited for use in clinical settings.