Prevalence of variant CJD agent in Britain remains uncertain

Research: Prevalence of disease related prion protein in anonymous tonsil specimens in Britain: Cross-sectional opportunistic survey – First results from a large tissue survey in Britain of the agent that causes variant Creutzfeldt-Jakob disease (vCJD) are unable so far to establish that the prevalence is lower than that given by previous estimates, concludes a study published on bmj.com.

vCJD prion protein found in a patient with haemophilia at post mortem

Evidence of infection with the agent (abnormal prion protein) that causes variant Creutzfeldt-Jakob Disease (vCJD) has been found at post mortem in the spleen of a person with haemophilia. – The patient, who was over 70 years old, died of a condition unrelated to vCJD and had shown no symptoms of vCJD or any other neurological condition prior to his death. The vCJD abnormal prion protein was only identified during post mortem research tests.

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