Virus Archives

AIDS drugs may prevent vaginal transmission of HIV

There are 33 million people infected with HIV. This study is a highly significant breakthrough because it offers proof-of-principle that pre-exposure prophylaxis with currently available anti-retroviral drugs can potentially prevent vaginal HIV transmission, empowering women throughout the world to protect themselves from this deadly disease. – Prescription drugs now used to treat human immunodeficiency virus infection in adults may prevent the vaginal transmission of HIV, researchers at UT Southwestern Medical Center have found.

Bird flu alert in West Bengal, India

Health officials in India are concerned there may be a possible major bird-flu outbreak after nearly 20000 chickens died in the past week. – Death of poultry birds has been reported from parts of Birbhum and South Dinajpur districts of West Bengal, India.

273 human proteins required for HIV propagation

Using a technique called RNA interference to screen thousands of genes, researchers identified 273 human proteins required for HIV propagation. The vast majority had not been connected to the virus by previous studies. – Current drugs attack HIV itself, leaving patients vulnerable to counterattack by the rapidly mutating virus, which often evolves resistance. But the human proteins exploited by HIV represent potential therapeutic targets that could avoid this problem. The challenge will be to develop drugs that inhibit HIV by interacting with these human proteins without hurting our cells.

Protein may trigger insulin production in diabetic patients

University of Florida researchers have coaxed liver and pancreatic cells within diabetic mice into churning out insulin by injecting the animals with a naturally occurring protein called Pdx1, opening up a new research avenue that someday could lead to safer treatments for type 1 diabetes. Pdx1 activates the genes controlling the development of the pancreas cells that make and release insulin to maintain safe levels of glucose in the body. – If the human body were a stage, then proteins would rank among the lead actors in the play we call “Life.” These large biological molecules hold many starring roles, and their lines are dictated by information encoded in our genes. They are production powerhouses, regulating the basic processes of living and controlling countless functions. Many are enzymes that produce or use energy. Others regulate genes.

New test to detect and identify 12 respiratory viruses

The U.S. Food and Drug Administration cleared for marketing a test – xTAG Respiratory Viral Panel, manufactured by Luminex Molecular Diagnostics, that simultaneously detects and identifies 12 specific respiratory viruses. – The U.S. Food and Drug Administration has approved a new diagnostic test that detects 12 respiratory viruses, including strains of flu that have triggered epidemics.

New strategies work to put cancer on the firing line

Cancer cells are our own cells gone awry. That means our immune system doesn?t always see cancer as a horrific invader. – Dr. Yukai He wants to put cancer in the bull’s eye. “Cancer really comes from us,” the Medical College of Georgia Cancer Center immunologist says of the scary reality that cancer cells are our own cells gone awry. That means our immune system doesn’t always see cancer as a horrific invader.

Three more H5N1 bird flu deaths in Egypt

Egyptian officials announced two new deaths from H5N1 avian influenza in women from the Nile Delta, along with what appears to be a third death involving a 50-year-old woman. – Two new deaths from H5N1 avian influenza in women from the Nile Delta reported by Egyptian officials, and a third death involving a 50-year-old woman whose infection was previously confirmed by the World Health Organization (WHO).

Mouth rinse gargle test for cancer

A simple mouth rinse may provide a new way to screen for head and neck cancers in people at high risk for these diseases. – A morning gargle could someday be more than a breath freshener ? it could spot head and neck cancer, say scientists at the Johns Hopkins Kimmel Cancer Center. Their new study of a mouth rinse that captures genetic signatures common to the disease holds promise for screening those at high risk, including heavy smokers and alcohol drinkers.

New warning for nonoxynol 9 OTC contraceptives in US

Nonoxynol 9 or N9 in the widely available stand-alone contraceptive products do not protect against sexually transmitted diseases, including HIV infection. – The U.S. Food and Drug Administration (FDA) issued a final rule that requires that manufacturers of over-the-counter (OTC) stand-alone vaginal contraceptive and spermicidal products containing the chemical ingredient nonoxynol 9 (N9) include a warning that the chemical N9 does not provide protection against infection from HIV (the virus that causes AIDS) or other sexually transmitted diseases (STDs).

Combination therapy and antibiotics may help multiple sclerosis patients

Combining a medication currently used to treat multiple sclerosis with an antibiotic may slow the progress of the disease in multiple sclerosis patients.
– A preliminary study suggests that combining a medication currently used to treat multiple sclerosis with an antibiotic may slow the progress of the disease, according to an article posted online today that will appear in the February 2008 print issue of Archives of Neurology, one of the JAMA/Archives journals.

Ebola virus outbreak in Uganda worsens, says WHO

The number of suspected cases of Ebola haemorrhagic fever in western Uganda has almost doubled in the past 10 days, and four health-care workers are now among the fatalities, the United Nations World Health Organization (WHO) reported.
– The number of suspected cases of Ebola haemorrhagic fever in the Bundibugyo District of western Uganda has now risen to 93, including 22 fatalities. Laboratory analysis has confirmed the presence of a new species of the virus in 9 of these cases.

Stars in Sierre Leone AIDS awareness campaign

For a new AIDS awareness advertising campaign in Sierra Leone, Manchester United stars Ryan Giggs, Rio Ferdinand and Patrice Evra have joined forces with UNICEF
– Manchester United stars Ryan Giggs, Rio Ferdinand and Patrice Evra have joined forces with UNICEF to front a new AIDS awareness advertising campaign in Sierra Leone.