Overweight, obese women improve life with short exercise

Sedentary, overweight or obese women can improve their quality of life by exercising as little as 10 to 30 minutes a day, researchers reported. – Sedentary, overweight or obese women can improve their quality of life by exercising as little as 10 to 30 minutes a day, researchers reported at the American Heart Association’s Conference on Nutrition, Physical Activity and Metabolism.

GSK investigation concludes, says MHRA, UK

Professor Kent Woods, MHRA Chief Executive, said: ?I remain concerned that GSK could and should have reported this information earlier than they did.” – The Medicines and Healthcare products Regulatory Agency (MHRA) has concluded its four year investigation into Glaxosmithkline and its antidepressant drug Seroxat. The investigation focused on whether GSK had failed to inform the MHRA of information it had on the safety of Seroxat in under 18’s in a timely manner.

Psychological distress linked to increased risk of stroke

Psychological distress, but not depression, may increase the risk of stroke. Previous studies have shown that stroke often leads to depression, but the evidence was mixed as to whether depression could lead to stroke. – Psychological distress, but not depression, may increase the risk of stroke, according to a study published in the March_4, 2008, issue of Neurology, the medical journal of the American Academy of Neurology. Previous studies have shown that stroke often leads to depression, but the evidence was mixed as to whether depression could lead to stroke.

Antidepressant and psychotherapy work for depressed teens

Antidepressant and psychotherapy work for depressed teens

Teens with treatment-resistant depression more likely to get better with switch to combination therapy – antidepressant and psychotherapy. – Teens with difficult-to-treat depression who do not respond to a first antidepressant medication are more likely to get well if they switch to another antidepressant medication and add psychotherapy rather than just switching to another antidepressant, according to a large, multi-site trial funded by the National Institutes of Health’s National Institute of Mental Health (NIMH).

Antidepressants only benefit severely depressed patients

Antidepressant medications appear to help only severely depressed people, a new analysis has found. – Who benefits from antidepressant drugs? A new study from from the University of Hull published today in PLoS Medicine suggests that antidepressant medicines only benefit some, very severely depressed patients.

Aquatic exercise could benefit fibromyalgia sufferers

The addition of an aquatic exercise programme to the usual care for fibromyalgia in women, is cost-effective in terms of both health care costs and societal costs. – Patients suffering from fibromyalgia could benefit significantly from regular exercise in a heated swimming pool, a study published today in the open access journal Arthritis Research & Therapy shows. The findings suggest a cost effective way of improving quality of life for patients with this often-debilitating disorder.

Depression and anxiety can double heart disease risk

Anxiety and depression are associated with mechanisms that promote atherosclerosis. Most recent studies of emotional disturbances in coronary artery disease (CAD) have focused on depression only. Anxiety and depression predict greater MACE (Major adverse cardiac events) risk in patients with stable CAD (Coronary Artery Disease). – Matters of the mind can affect matters of the heart. A new study from Universit? de Montr?al and McGill University researchers has found that major anxiety and/or depression, can double a coronary artery disease patient’s chances of repeated heart ailments. This is one of the first studies to focus on patients with stable coronary artery disease ? not those who were hospitalized for events such as a heart attack.

NEJM Antidepressant’s Publication study may discourage depressed people

Mental Health America response to New England Journal of Medicine Study, “Selective Publication of Antidepressant Trials and Its Influence on Apparent Efficacy”. – Mental Health America notifies the potential harm of the NEJM’s Selective Publication of Antidepressant Trials study that it may discourage people with depression from seeking appropriate care and evidence-based treatments that work for them. Mental Health America is one of America’s leading mental health advocacy groups.

Selective reporting of antidepressant trials may have adverse consequences

Evidence-based medicine is valuable to the extent that the evidence base is complete and unbiased. Selective publication of clinical trials ? and the outcomes within those trials ? can lead to unrealistic estimates of drug effectiveness and alter the apparent risk?benefit ratio. – Selective publication in reporting results of antidepressant trials exaggerates the effectiveness of the drugs, and may have adverse consequences for researchers, study participants, health care professionals, and patients, revealed in a new study.

Exercise gene could help with depression

Boosting an exercise-related gene in the brain works as a powerful anti-depressant ? a finding that could lead to a new antidepressant drug target.
– Boosting an exercise-related gene in the brain works as a powerful anti-depressant in mice – a finding that could lead to a new anti-depressant drug target, according to a Yale School of Medicine report in Nature Medicine.

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