RNA may stop breast cancer spread

The identification of molecules that inhibit a cell’s metastatic potential may help guide clinical decision-making in the future by enabling oncologists to more accurately identify patients at highest risk for metastatic relapse. – Now, researchers can develop more effective drugs to prevent or treat cancer metastasis, as they have identified a specific group of microRNA molecules that are responsible for controlling genes that cause breast cancer metastasis.

Colonoscopy fears overcome when patients support patients

University of Pennsylvania School of Medicine researchers found that patients who received telephone mentoring from a trained “peer coach” were two times more likely to keep their first colonoscopy appointment than those who received an educational brochure about the procedure in the mail or received no peer or literature support. – Patients who have had a colonoscopy can play a life-saving role by encouraging other patients to follow through with their own colorectal cancer screenings, according to new research from the University of Pennsylvania School of Medicine. These peer coaches can provide important information to combat myths and fears that serve as barriers to colonoscopy ? issues patients say their doctors often fail to address.

Lung cancer cells’ survival gene 14-3-3zeta seen as drug target

Lung cancer cells’ survival gene 14-3-3zeta seen as drug target, as lung cancer cells can?t survive on their own when this key gene called 14-3-3zeta is silenced. – One of the deadliest forms of cancer appears to carry a specific weakness. When a key gene called 14-3-3zeta is silenced, lung cancer cells can’t survive on their own, researchers have found.

Novel anti-cancer strategy moves to clinic

Emory University researchers have developed a novel anti-tumor compound that represents a distinct strategy: targeting one of the most important “intercept points” for cancer cells. – Researchers at Emory University have developed a novel anti-tumor compound that represents a distinct strategy: targeting one of the most important “intercept points” for cancer cells.

New strategies work to put cancer on the firing line

Cancer cells are our own cells gone awry. That means our immune system doesn?t always see cancer as a horrific invader. – Dr. Yukai He wants to put cancer in the bull’s eye. “Cancer really comes from us,” the Medical College of Georgia Cancer Center immunologist says of the scary reality that cancer cells are our own cells gone awry. That means our immune system doesn’t always see cancer as a horrific invader.

Mouth rinse gargle test for cancer

A simple mouth rinse may provide a new way to screen for head and neck cancers in people at high risk for these diseases. – A morning gargle could someday be more than a breath freshener ? it could spot head and neck cancer, say scientists at the Johns Hopkins Kimmel Cancer Center. Their new study of a mouth rinse that captures genetic signatures common to the disease holds promise for screening those at high risk, including heavy smokers and alcohol drinkers.

Breast cancer gene mutation common in Hispanic, young black women

The gene mutation BRCA1, which is known to increase the risk of breast cancer, is prevalent among Hispanics and young black women with breast cancer, researchers report. – A genetic mutation already known to be more common in Ashkenazi Jewish breast cancer patients is also prevalent in Hispanic and young African-American women with breast cancer, according to one of the largest, multiracial studies of the mutation to date.

Test for targeted therapy in acute myeloid leukemia

Researchers have discovered that a particular hormone is responsible for driving a cancer enzyme to cause an often deadly red blood cell cancer, Polycythemia vera.
– An Oregon Health & Science University Cancer Institute researcher has discovered that a particular hormone is responsible for driving a cancer enzyme to cause an often deadly red blood cell cancer.

Gleevec improves special leukemia in children

Gleevec has been shown to improve outcomes for children with Philadelphia chromosome-positive acute lymphoblastic leukemia.
– Gleevec, the targeted cancer pill that has saved more than 100,000 lives, now is saving more children with a dire leukemia, as well as preventing disease progression with long term use in adults with chronic myeloid leukemia.

Understanding chronic myeloid leukemia

Researchers have discovered abnormal cells in the early stem cell population in Chronic myeloid leukemia CML patients.
– Oregon Health & Science University Cancer Institute researchers have opened a new window into the roots of chronic myeloid leukemia (CML). “We are looking under the surface of CML to understand better where the cancer is coming from. We have discovered abnormal cells in the early stem cell population in some CML patients, which don’t belong to the CML clone. These are abnormal cells that are not part of the CML clone,” said Thomas Bumm, M.D., OHSU Cancer Institute member.

Night shift work may cause cancer

World Health Organization study found that night shift work increases the risk of cancer in humans. Women are at a higher risk to develop breast and colon cancer and men more likely to experience prostate cancer.
– A study by the World Health Organization has found that night shift work increases the risk of cancer in humans. The study found that after prolonged exposure to night shift work, women are at a higher risk to develop breast and colon cancer. Men who work the night shift are more likely to experience prostate cancer.

New perspectives on health disparities in breast cancer research

Asian breast cancer women (67.5 percent) choose to have a mastectomy over lumpectomy compared to Caucasian women (57.3 percent).
– Breast cancer is a disease with a number of known genetic and behavioral risk factors, but scientists have seen that these risks are often compounded by social and racial inequalities. The question remains: how, exactly, do social disadvantages, genetics, race and culture add to the disparities faced by so many groups of women?

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