FDA declines Fusilev NDA for colorectal cancer

Spectrum Pharmaceuticals Receives Complete Response Letter from FDA for FUSILEV(R) in Advanced Metastatic Colorectal Cancer – A Complete Response letter is issued by the U.S. Food and Drug Administration (FDA) regarding the supplemental New Drug Application (sNDA) for FUSILEV (levoleucovorin) for injection for treatment of patients with advanced metastatic colorectal cancer.

Young women with colon cancer lived longer than men

Women fare better than men with metastatic colorectal cancer — are hormones helping? – Younger women with metastatic colorectal cancer lived longer than younger men, revealed by researchers in a new US study. However, this survival advantage disappeared with age, suggesting a benefit from estrogen or other hormones.

New treatment for melanoma shows shrinking of tumors

Trial of new treatment for advanced melanoma shows rapid shrinking of tumors – Researchers have made significant advances in the treatment of metastatic malignant melanoma ? one of the most difficult cancers to treat successfully once it has started to spread.

New blood test promise diagnosis of colon cancer

New blood tests promise simple, cost-effective diagnosis of gastrointestinal cancers – Promising results from a new blood test that can aid in the early identification of patients with colon cancer will be presented at Europe’s largest cancer congress, in Berlin today.

Cetuximab for colorectal cancer with KRAS gene

Cost-effectiveness of cetuximab in metastatic colorectal cancer – From a health-care system perspective, it may be more efficient to use the drug cetuximab only in colorectal cancer patients whose tumors have a wild-type KRAS gene, according to a study published online August 7 in the Journal of the National Cancer Institute.

Thalidomide does not improve survival in lung cancer

JNCI news brief: Thalidomide does not improve survival in small cell lung cancer – Treating patients with thalidomide in combination with chemotherapy for small cell lung cancer (SCLC) did not improve their survival but did increase their risk of blood clots, revealed by researchers.

CT colonography better for colorectal cancer screening

Less invasive CT-scan based colorectal cancer screening method shows good accuracy – Computed tomographic (CT) colonography may offer patients at increased risk of colorectal cancer an alternative to colonoscopy that is less-invasive, is better-tolerated and has good diagnostic accuracy.

Evaluating risk factors of sporadic colorectal cancer

What are the risk factors of sporadic colorectal cancer? – Colorectal cancer (CRC) is one of the most common cancers in China. Although the association between the epidemiological factors and sporadic colorectal cancer is not known and still remains uncertain.

Colorectal cancer rising in young adults 20-29 years in US

Study says colorectal cancer increasing in young adults – largest annual percent increase in colorectal cancer incidence was in the youngest age group 20-29 years – A new study finds that in sharp contrast to the overall declining rates of colorectal cancer in the United States, incidence rates among adults younger than age 50 years are increasing.

Advance in bowel cancer test research – gene expression biomarkers

Gene expression biomarkers can accurately discriminate pre-cancerous and cancerous colorectal growths. – Australian researchers have developed gene expression biomarkers which can accurately discriminate pre-cancerous and cancerous colorectal growths from non-cancerous controls.

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