Surgery not necessary for most late stage colorectal cancers

Patients with advanced colorectal cancer spreaded to other organs (stage IV) don’t require immediate surgery. – A new study shows that a large majority of patients who present with advanced colorectal cancer that has spread to other organs (stage IV) don’t require immediate surgery to remove the primary tumor in the colon.

Hormone therapy reduces woman’s risk of colorectal cancer by 40%

Hormone therapy offers potential protective effect against colon cancer in older women – In a large study, a national team of researchers led by Mayo Clinic scientists observed that self-reported use of hormone therapy was associated with a significantly lower colorectal cancer risk. However, the mechanisms for the apparent protective association are still unclear.

Benefits from screening colonoscopy limited

Annals colonoscopy study underscores importance of quality standards. Cancer of the colon should be one of the easiest tumors to prevent. – Screening colonoscopy is associated with fewer deaths from colorectal cancer, and the association is primarily limited to deaths from cancer developing in the left side of the colon, revealed by researchers.

Smoking increases colorectal cancer risk

Colorectal cancer is the third most common form of cancer and the fourth most frequent cause of cancer deaths worldwide. Cigarette smoking is significantly associated with colorectal cancer incidence and mortality. – An analysis of previous studies indicates that smoking is significantly associated with an increased risk for colorectal cancer and death, according to an article in the December 17 issue of JAMA.

Colonoscopy’s limitation for right sided colon cancer

Colonoscopy significantly reduces death from left-sided colon cancer but not from right-sided. Physicians should advise patients of test limitations. – A new study finds that colonoscopy is strongly associated with fewer deaths from colorectal cancer. However, the risk reduction appears to be entirely due to a reduction in deaths from left-sided cancers.

Colorectal cancer rate declines in US

ASGE encouraged by drop in colorectal cancer deaths. Prevention through screening and removal of precancerous polyps among key factors in saving lives. – The American Society for Gastrointestinal Endoscopy (ASGE) heralds the recent news of a decline in U.S. cancer deaths and incidence rates, with colorectal cancer among the top three cancers with significant declines.

Colonoscopy associated with reduced colorectal cancer incidence

Study confirms colonoscopy associated with reduced colorectal cancer incidence. Incidence reduction in the proximal colon differs in magnitude and timing. – Patients who undergo a complete negative colonoscopy have a reduced incidence of colorectal cancer, confirms a study published in Clinical Gastroenterology and Hepatology.

Colon cancer’s genetic link to obesity

JAMA study a first to connect obesity, genetics and colon cancer risk. Gene variation associated with decreased risk of colorectal cancer. – A new study reveals the first-ever genetic link between obesity and colon cancer risk, a finding that could lead to greater accuracy in testing for the disease, said a researcher at the University of Alabama at Birmingham (UAB).

CT colonography a viable colorectal cancer screening option

Colonoscopy still the definitive test for colorectal cancer screening and prevention. – Death from colorectal cancer is highly preventable with effective screening and early detection. Many screening options are available, each with advantages and disadvantages, but half of eligible patients still do not participate in colorectal cancer screening.

A genetic trait identified for colorectal cancer risk

About one-third of colorectal cancers are inherited, but the genetic cause of most of these cancers is unknown. The genes linked to colorectal cancer account for less than 5 percent of all cases. – Scientists at Northwestern University’s Feinberg School of Medicine and colleagues have discovered a genetic trait that is present in 10 to 20 percent of patients with colorectal cancer. The findings strongly suggest that the trait is a major contributor to colorectal cancer risk and likely the most common cause of colorectal cancer to date.

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