New chemical tool kit reveals insights into drug toxicity

A Harvard Medical School team led by Vamsi Mootha has developed a new chemical tool kit that helps in explaining how drugs can affect its users, reveals insights into drug toxicity. – Why do nearly 1 million people taking cholesterol-lowering statins often experience muscle cramps? Why is it that in the rare case when a diabetic takes medication for intestinal worms, his glucose levels improve? Is there any scientific basis for the purported health effects of green tea?

Gastric acid protects against foodborne diseases

Gastric acid protects against foodborne diseases

Low levels of gastric acid in the stomach can increase one?s likelihood of getting a foodborne infection. – A new study suggests that low levels of gastric acid in the stomach can increase one’s likelihood of getting a foodborne infection. The researchers from Australia report their findings in the February 2008 issue of the journal Infection and Immunity.

Reducing kids’ salt intake lowers soft drink consumption

A reduction in salt intake could play a role in helping to reduce childhood obesity through its effect on sugar-sweetened soft drink consumption. – Children who eat less salt drink fewer sugar-sweetened soft drinks and may significantly lower their risks for obesity, elevated blood pressure and later-in-life heart attack and stroke, researchers reported in the print and online issue of Hypertension: Journal of the American Heart Association.

Genetic breakthrough boosting natural immunity

Genetic breakthrough supercharges immunity to flu and other viruses; McGill researchers discover way to boost cells’ natural anti-virus defences. – Researchers at McGill University have discovered a way to boost an organism’s natural anti-virus defences, effectively making its cells immune to influenza and other viruses.

US’ 49 states gripped with influenza

Influenza activity has been picking up in the US; flu widespread in 49 states, CDC reports. – After relatively low levels of influenza activity in the early part of the season, since January influenza activity has been picking up in the US. This week 44 states are reporting widespread influenza activity. This is up from 31 states reporting widespread activity last week. Five states are reporting regional activity, making 49 states overall.

Duragesic 25 mcg/hr CII pain patches recalled

PriCara, Division of Ortho-McNeil-Janssen Pharmaceuticals, Inc. said that all lots of 25 microgram/hour (mcg/hr) DURAGESIC (fentanyl transdermal system) CII patches sold by PriCara in the United States and all 25 mcg/hr fentanyl patches sold by Sandoz Inc. in the United States are being voluntarily recalled as a precaution from wholesalers and pharmacies. – DURAGESIC 25 mcg/hr (fentanyl transdermal system) CII patches for pain have been recalled because of a cut along one side of the drug reservoir within the patch. Fentanyl patches that are cut or damaged in any way may lead to serious adverse events.

Most with high blood pressure do not follow DASH diet

The dietary profile of adults with HTN (Hypertension) in the United States has a low accordance with the (Dietary Approaches to Stop Hypertension) DASH dietary pattern, and the dietary quality of adults with HTN has deteriorated since the introduction of the DASH diet, suggesting that secular trends have minimized the impact of the DASH message. – A relatively small proportion of individuals with hypertension (high blood pressure) eat diets that align with government guidelines for controlling the disease, according to a report in the February 11 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

Update on Avian Influenza in West Bengal, India

No suspected human cases of Avian Influenza have been detected in any of the affected Districts. – No suspected human cases of Avian Influenza have been detected in any of the affected districts in West Bengal, in India. Number of affected districts (14 districts) remains the same. In these districts, 48 blocks and five municipalities are involved.

7 new prostate cancer genetic risk factors identified

UK researchers identified more than 7 new genetic links to prostate cancer, 2 of which would be included in a new diagnostic test aimed at spotting men at risk from this disease. – 7 new sites in the human genome identified that are linked to men’s risk of developing prostate cancer, revealed by Cancer Research UK funded scientists at the Institute of Cancer Research and University of Cambridge.

IGFBP7 protein may stop melanoma skin cancer

One might call it a tale of two melanocytes. Given the same genetic mutation, why does one melanocyte shut down growth and become a relatively benign mole, while another rages out of control and develops into deadly melanoma” – Howard Hughes Medical Institute (HHMI) researchers have uncovered a protein that stops the growth of melanoma, a cancer that develops from pigment-producing cells in the skin called melanocytes.

Acupuncture during IVF improves pregnancy chances

Acupuncture given within one day of IVF with embryo transfer improves rates of pregnancy and live birth among women undergoing in vitro fertilisation cycle (IVF), revealed by US researchers. – Acupuncture given with embryo transfer improves rates of pregnancy and live birth among women undergoing in vitro fertilisation cycle (IVF), revealed by US researchers. Acupuncture given within one day of IVF proved beneficial.

Strong genetic influence on childhood obesity

Evidence for a strong genetic influence on childhood adiposity despite the force of the obesogenic environment. – A British study reveals that obesity in children is not only because of lack of exercise and wrong dietary habits, but there is a strong genetic influence amongst other factors that lead to childhood obesity.

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