Neratinib shows promise in trastuzumab resistant breast cancer

Small molecule inhibitor shows promise in trastuzumab-resistant metastatic breast cancer – Fox Chase Cancer Center researchers report that a combination of trastuzumab and neratinib (HKI-272) a novel small molecule inhibitor of the HER2 receptor (ErbB2) appears active in women with HER2-positive metastatic breast cancer who have progressed on previous trastuzumab based therapies.

Pregnant should gain a healthy weight before and during pregnancy

Report updates guidelines on how much weight women should gain during pregnancy – Calls on health care providers to help women achieve a healthy weight before and during pregnancy. – A growing amount of scientific evidence indicates that how much weight women gain during pregnancy and their starting weight at conception can affect their health and that of their babies, says a new report from the Institute of Medicine and the National Research Council.

Statins may help prevent stroke recurrence

Cholesterol-lowering drugs statins may help prevent stroke recurrence. – People who take cholesterol-lowering drugs called statins after a stroke may be less likely to have another stroke later, according to research published in the May 26, 2009, print issue of Neurology, the medical journal of the American Academy of Neurology.

Infertility linked to genes for earlier menopause

Identification of genetic variants affecting age at menopause could help improve fertility treatment – For the first time, scientists have been able to identify genetic factors that influence the age at which natural menopause occurs in women. Ms Lisette Stolk, a researcher from Erasmus MC, Rotterdam, The Netherlands, told the annual conference of the European Society of Human Genetics that a greater understanding of the factors influencing age at menopause might eventually help to improve the clinical treatment of infertile women.

Healthy lifestyle is on decline in US

Following a healthy lifestyle is on the decline in the US – Researchers urge individuals to adopt healthier lifestyles, particularly in middle age. – Despite the well-known benefits of having a lifestyle that includes physical activity, eating a diet high in fruits and vegetables, maintaining a healthy weight, moderate alcohol use and not smoking, only a small proportion of adults follow this healthy lifestyle pattern, and in fact, the numbers are declining, according to an article published in the June 2009 issue of The American Journal of Medicine.

Shared genetic link between dental disease periodontitis and heart attack

Scientists find shared genetic link between the dental disease periodontitis and heart attack – The relationship between the dental disease periodontitis and coronary heart disease (CHD) has been known for several years. Although a genetic link seemed likely, until now its existence was uncertain.

A breakthrough in floppy baby syndrome research

Australian team reveals world-first discovery in a ‘floppy baby’ syndrome – In a world first, West Australian scientists have cured mice of a devastating muscle disease that causes a Floppy Baby Syndrome ? a breakthrough that could ultimately help thousands of families across the globe.

Body mind training technique reduces stress

Of body and mind, and deep meditation – Chinese data unraveled at University of Oregon show a training technique has brain, physiological linkage. – Chinese researchers have unlocked the mechanism of an emerging mind-body technique that produces measurable changes in attention and stress reduction in just five days of practice.

Excessive cola consumption can lead to muscle problems

Excessive cola consumption can lead to super-sized muscle problems warn doctors – Doctors have issued a warning about excessive cola consumption after noticing an increase in the number of patients suffering from muscle problems, according to the June issue of IJCP, the International Journal of Clinical Practice.

Genetic factors may predict depression in heart disease patients

Genetic variations contribute to depression in heart disease patients. – Individuals with heart disease are twice as likely to suffer from depression as the general population, an association the medical community has largely been unable to explain. Now, a new study by researchers at The Miriam Hospital, in conjunction with The Montr?al Heart Institute, University of Montr?al and McGill University, reveals there may be genetic variations that contribute to depression in heart disease patients.

Cardiorespiratory fitness lowers heart disease risk

Better Cardiorespiratory Fitness Related to Lower Risk of Death, Cardiovascular Disease – Persons with higher levels of cardiorespiratory fitness have a lower risk of all-cause death and coronary heart disease and cardiovascular disease compared to persons with lower levels of cardiorespiratory fitness, according to an analysis of previous studies appearing in the May 20 issue of JAMA.

Bone marrow cell therapy for ischemic heart disease patients

Bone marrow cell therapy may be beneficial for patients with ischemic heart disease – The injection of bone marrow cells into the heart of patients with chronic myocardial ischemia (reduced blood flow to some areas of the heart) was associated with modest improvements in blood flow and function of the left ventricle, according to a study in the May 20 issue of JAMA.

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