New blood test predicts breast cancer risk

New test predicts the risk of non-hereditary breast cancer — A simple blood test is currently in development that could help predict the likelihood of a woman developing breast cancer – A simple blood test is currently in development that could help predict the likelihood of a woman developing breast cancer, even in the absence of a high-risk BRCA1 gene mutation. This new research is published in the Genome Medicine.

Biomarker CA-125 shows promise as screening tool for early detection of ovarian cancer

CA-125 change over time shows promise as screening tool for early detection of ovarian cancer — Blood test used to find recurrence uncovers invasive, high-grade disease at curable stage – CA-125, the protein recognized for predicting ovarian cancer recurrence, now shows promise as a screening tool for early-stage disease of ovarian cancer. The simple blood test could offer a much-needed screening tool to detect ovarian cancer in its early stages – even in the most aggressive forms.

Aspirin reduces aggressive ovarian cancer risk

Aspirin may decrease risk of aggressive form of ovarian cancer – New research shows that women who regularly use pain relief medications, particularly aspirin, have a decreased risk of serous ovarian cancer?an aggressive carcinoma affecting the surface of the ovary, published in Acta Obstetricia et Gynecologica Scandinavica.

Breast cancer’s genetic causes provide clues for new therapeutic targets

UNC Lineberger scientists lead cancer genome analysis of breast cancer — Team identifies genetic causes and similarity to ovarian cancer – The researchers, including a large group from the University of North Carolina at Chapel Hill, reported their study about genetic characterization of 800 breast tumors, finding some of the genetic causes of the most common forms of breast cancer, providing clues for new therapeutic targets, and identifying a molecular similarity between one sub-type of breast cancer and ovarian cancer.

Chemotherapy resistance develops due to WNT in cancer patients

Researchers discover new mechanism behind resistance to cancer treatment — Finding could lead to development of better therapies to cure cancer – Developing resistance to chemotherapy is a nearly universal, ultimately lethal consequence for cancer patients with solid tumors ? such as those of the breast, prostate, lung and colon ? that have metastasized, or spread, throughout the body.

Increasing height and body mass index linked to ovarian cancer risk

Increasing height and body mass index are risk factors for ovarian cancer – Increasing height and, among women who have never taken menopausal hormone therapy, increased body mass index are risk factors for developing ovarian cancer in women, revealed by researchers.

Antibody may cure variety of human cancers

Single antibody shrinks variety of human tumors transplanted into mice, Stanford study shows – Human tumors transplanted into laboratory mice disappeared or shrank when scientists treated the animals with a single antibody. This antibody works by masking a protein flag on cancer cells that protects them from macrophages and other cells in the immune system.

$3.5 million Komen award to study rare and aggressive type of breast cancer

TGen breast cancer research benefits from $3.5 million Komen award — Grant enables multi-institute team to study rare and aggressive type of breast cancer – The Translational Genomics Research Institute (TGen) is part of a team of medical investigators receiving a $3.5 million grant from Susan G. Komen for the Cure to study triple-negative breast cancer, a highly aggressive form of this cancer that disproportionately affects African-Americans.

Ovarian cancer screening does not improve survival

Ovarian cancer screening does not appear to reduce risk of ovarian cancer death – In a clinical trial that included nearly 80,000 women, those who received ovarian cancer screening did not have a reduced risk of death from ovarian cancer compared to women who received usual care, but did have an increase in invasive medical procedures and associated harms as a result of being screened.

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