New test predicts the risk of non-hereditary breast cancer — A simple blood test is currently in development that could help predict the likelihood of a woman developing breast cancer – A simple blood test is currently in development that could help predict the likelihood of a woman developing breast cancer, even in the absence of a high-risk BRCA1 gene mutation. This new research is published in the Genome Medicine.
Research backs risk-reduction surgery for ovarian cancer – Scientists back preventative surgery to improve survival for women who are at greater risk of getting ovarian cancer and suggest it appears helpful for women at risk of getting breast cancer because of genetic faults.
CA-125 change over time shows promise as screening tool for early detection of ovarian cancer — Blood test used to find recurrence uncovers invasive, high-grade disease at curable stage – CA-125, the protein recognized for predicting ovarian cancer recurrence, now shows promise as a screening tool for early-stage disease of ovarian cancer. The simple blood test could offer a much-needed screening tool to detect ovarian cancer in its early stages – even in the most aggressive forms.
Aspirin may decrease risk of aggressive form of ovarian cancer – New research shows that women who regularly use pain relief medications, particularly aspirin, have a decreased risk of serous ovarian cancer?an aggressive carcinoma affecting the surface of the ovary, published in Acta Obstetricia et Gynecologica Scandinavica.
UNC Lineberger scientists lead cancer genome analysis of breast cancer — Team identifies genetic causes and similarity to ovarian cancer – The researchers, including a large group from the University of North Carolina at Chapel Hill, reported their study about genetic characterization of 800 breast tumors, finding some of the genetic causes of the most common forms of breast cancer, providing clues for new therapeutic targets, and identifying a molecular similarity between one sub-type of breast cancer and ovarian cancer.
Researchers discover new mechanism behind resistance to cancer treatment — Finding could lead to development of better therapies to cure cancer – Developing resistance to chemotherapy is a nearly universal, ultimately lethal consequence for cancer patients with solid tumors ? such as those of the breast, prostate, lung and colon ? that have metastasized, or spread, throughout the body.
Increasing height and body mass index are risk factors for ovarian cancer – Increasing height and, among women who have never taken menopausal hormone therapy, increased body mass index are risk factors for developing ovarian cancer in women, revealed by researchers.
The path to personalized cancer treatment — Researchers identify genetic markers of drug sensitivity in cancer cells – Recently researchers have profiled genetic changes in cancer with drug sensitivity in order to develop a personalised approach to cancer treatments. They uncovered hundreds of associations between mutations in cancer genes and sensitivity to anticancer drugs.
Single antibody shrinks variety of human tumors transplanted into mice, Stanford study shows – Human tumors transplanted into laboratory mice disappeared or shrank when scientists treated the animals with a single antibody. This antibody works by masking a protein flag on cancer cells that protects them from macrophages and other cells in the immune system.
TGen breast cancer research benefits from $3.5 million Komen award — Grant enables multi-institute team to study rare and aggressive type of breast cancer – The Translational Genomics Research Institute (TGen) is part of a team of medical investigators receiving a $3.5 million grant from Susan G. Komen for the Cure to study triple-negative breast cancer, a highly aggressive form of this cancer that disproportionately affects African-Americans.