The scientific study of the nature of disease and its causes, processes, development, and consequences. Also called pathobiology.
Function found for Alzheimer’s protein — amyloid precursor protein (APP) – A new study reveals that when amyloid precursor protein (APP) fails to convert iron from an unsafe form to a safe one for transport or storage, it leads to rise in iron levels inside neurons mount to toxic levels and eventually causes Alzheimer’s disease.
Rheumatoid arthritis signaling protein reverses Alzheimer’s disease in mouse modeln — New study shows GM-CSF reduces AD pathology and eliminates memory loss – A signaling protein released during rheumatoid arthritis dramatically reduced Alzheimer’s disease pathology and reversed the memory impairment of mice bred to develop symptoms of the neurodegenerative disease, a new study by the University of South Florida reports.
Molecular mechanism triggering Parkinson’s disease identified in Stanford study – Scientists at the Stanford University School of Medicine have identified a molecular pathway responsible for the death of key nerve cells whose loss causes Parkinson’s disease. This discovery not only may explain how a genetic mutation linked to Parkinson’s causes the cells’ death, but could also open the door to new therapeutic approaches for the malady.
Detection of breast cancer in screening mammography has improved over time – Researchers analyzing 2.5 million screening mammograms performed on nearly one million women found discrimination of cancerous from non-cancerous lesions improved over a nine-year period. Results of the study are published in the online edition of the journal Radiology.
More ‘good’ cholesterol is not always good for your health — HDL cholesterol can transform from good to bad actor in heart-disease process
– We’ve all heard about the importance of raising HDL, or the so-called “good” cholesterol, and lowering LDL, or “bad” cholesterol, to improve heart health. While we’ve come to assume HDL cholesterol is an inherently good thing, a new study shows that for a certain group of patients, this is not always the case.
New blood test for newborns to detect allergy risk – A simple blood test can now predict whether newborn babies are at high risk of developing allergies as they grow older, thanks to research involving the University of Adelaide.
Study finds Alzheimer’s disease link in eyes of children with Down syndrome — Findings may lead to eye tests for brain disease in Alzheimer’s and Down syndrome – Researchers are going to develop an innovative eye test for early detection of Alzheimer’s disease and Down syndrome. As they discovered the protein that forms plaques in the brain in Alzheimer’s disease also accumulates in the eyes of people with Down syndrome.
Researchers discover new approach for identifying smokers at highest risk for developing lung cancer – Researchers from Boston University School of Medicine (BUSM) in collaboration with investigators at the University of Utah, have discovered a new approach for identifying smokers at the highest risk for developing lung cancer.
Study reveals genetic link between mammographic density and breast cancer – A University of Melbourne study has revealed that certain breast cancer genetic variants increase mammographic density, confirming the link between mammographic breast density and breast cancer.
Severity of H1N1 influenza linked to presence of Streptococcus pneumoniae – The presence of the Streptococcus pneumoniae in samples that can be easily obtained in clinics and emergency rooms may predict risk of severe disease in H1N1 pandemic influenza.
Diabetes weakens your bones – The inflammatory molecule TNF-a may contribute to delayed bone fracture healing in diabetics, revealed by researchers. Diabetes, a condition where the body either does not produce enough, or respond to, insulin, affects at least 171 million people worldwide, a figure that is likely to double by 2030.
PCPs are front line defense in diagnosing serious illness in patients with acute lower back pain — ‘Red flag’ clinical features aid PCPs in screening patients for serious diseases. – Primary care physicians are front line defense in diagnosing serious illness in patients with acute lower back pain, revealed by researchers at The George Institute for International Health in Australia.
