Pathology

The scientific study of the nature of disease and its causes, processes, development, and consequences. Also called pathobiology.

Concussions may be related to Alzheimer’s disease

Are concussions related to Alzheimer’s disease? – A history of concussion involving at least a momentary loss of consciousness may be related to the buildup of Alzheimer’s-associated plaques in the brain, revealed by researchers in Neurology, the medical journal of the American Academy of Neurology.

Smoking may change genes in smokers

Smoking changes our genes – The fact that smoking means a considerable health risk is nowadays commonly accepted. New research findings from Uppsala University and Uppsala Clinical Research Center show that smoking alters several genes that can be associated with health problems for smokers, such as increased risk for cancer and diabetes.

Parkinson’s Biomarker Test has prognostic and diagnostic value in Parkinson’s Disease

Comprehensive Parkinson’s Biomarker Test Has Prognostic and Diagnostic Value, Penn Medicine Team Reports — First Biomarker Results from Parkinson’s Progression Markers Initiative Detect Differences in Subtypes of Parkinson’s Disease – The first biomarker results reported from the Parkinson’s Progression Markers Initiative (PPMI), showing that a comprehensive test of protein biomarkers in spinal fluid have prognostic and diagnostic value in early stages of Parkinson’s disease.

Copper triggers and enhances progression of Alzheimer’s disease

Copper identified as culprit in Alzheimer’s disease – Copper appears to be one of the main environmental factors that trigger the onset and enhance the progression of Alzheimer’s disease by preventing the clearance and accelerating the accumulation of toxic proteins in the brain.

Personalized Strategies to Reduce Cancer Overtreatment

Major Changes Urged for Cancer Screening and Treatment — Scientific Panel Recommends New Personalized Strategies to Reduce Cancer Overtreatment – To address the growing problem of people being overdiagnosed and overtreated for cancer, a group of scientists convened by the National Cancer Institute and chaired by a UC San Francisco breast cancer expert is proposing a major update of the way the nation approaches diseases now classified as “cancer.”

Cholesterol increases Alzheimer’s disease and Heart disease risks

Cholesterol increases risk of Alzheimer’s and heart disease – High levels of blood cholesterol increase the risk of both Alzheimer’s disease and heart disease, but it has been unclear exactly how cholesterol damages the brain to promote Alzheimer’s disease and blood vessels to promote atherosclerosis.

Buphenyl a possible drug for Alzheimer’s disease

Rush scientists identify buphenyl as a possible drug for Alzheimer’s disease – Buphenyl, an FDA-approved medication for hyperammonemia, may protect memory and prevent the progression of Alzheimer’s disease. Hyperammonemia is a life-threatening condition that can affect patients at any age. It is caused by abnormal, high levels of ammonia in the blood.

Breast cancer risk gene can be discovered by massively parallel sequencing

Breast cancer risk gene discovery fast tracked by new technology – massively parallel sequencing – A new technology is developed to fast track the discovery of a breast cancer risk gene and could assist in the discovery of other cancer genes. Now, breast cancer risk gene can be discovered using the latest genetic sequencing technology.

Antibody may cure variety of human cancers

Single antibody shrinks variety of human tumors transplanted into mice, Stanford study shows – Human tumors transplanted into laboratory mice disappeared or shrank when scientists treated the animals with a single antibody. This antibody works by masking a protein flag on cancer cells that protects them from macrophages and other cells in the immune system.

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