Too much cholesterol in the blood, or high blood cholesterol, can be serious. People with high blood cholesterol have a greater chance of getting heart disease. High blood cholesterol itself does not cause symptoms, so many people are unaware that their cholesterol level is too high.
US FDA approves new orphan drug Kynamro to treat inherited cholesterol disorder – Kynamro – mipomersen sodium – injection approved as an addition to lipid-lowering medications and diet to treat patients with a rare type of high cholesterol called homozygous familial hypercholesterolemia (HoFH). Kynamro is approved by the U.S. Food and Drug Administration.
Fasting Time Prior to Blood Lipid Tests Appears to Have Limited Association With Lipid Levels – Fasting prior to blood lipid tests appears to have limited association with lipid subclass levels, suggesting that fasting for routine lipid level determinations may be unnecessary.
Healthy diets have long-lasting positive effects even with partial weight regain – Mediterranean and low-carbohydrate diets have lasting, healthy effects, even with partial weight regain. The study is published in a peer-reviewed letter in the current New England Journal of Medicine (NEJM) as an update to the landmark study, the workplace-based Dietary Intervention Randomized Controlled Trial (DIRECT), a tightly controlled 24-month dietary intervention.
Study: Stroke becoming more common in young people – Stroke may be affecting people at a younger age, revealed by researchers. “The reasons for this trend could be a rise in risk factors such as diabetes, obesity and high cholesterol,” said study author Brett Kissela, MD, MS, with the University of Cincinnati College of Medicine in Ohio and a Fellow of the American Academy of Neurology.
FDA takes action against thousands of illegal Internet pharmacies — Agency participates in international Operation Pangea V to protect consumers from potentially dangerous, unapproved drugs – The U.S. Food and Drug Administration, in partnership with international regulatory and law enforcement agencies, took action this week against more than 4,100 Internet pharmacies that illegally sell potentially dangerous, unapproved drugs to consumers. Actions taken include civil and criminal charges, seizure of illegal products, and removal of offending websites.
‘Cafeteria diet’ hastens stroke risk — High-sugar, high-salt intake creates ‘a ticking time bomb of health problems’ – The fat- and sugar-rich Western diet leads to a lifetime of health problems, dramatically increasing the risk of stroke or death at a younger age,. Researchers found that a high-calorie, high-sugar, high-sodium diet nicknamed the ‘cafeteria diet’ induced most symptoms of metabolic syndrome ? a combination of high levels of cholesterol, blood sugar, blood pressure and obesity ? in rats after only two months.
Poor sleep in adolescents may increase risk of heart disease – Adolescents who sleep poorly may be at risk of cardiovascular disease in later life. “We found an association between sleep disturbance and cardiovascular risk in adolescents, as determined by high cholesterol levels, increased BMI [body mass index] and hypertension,” writes lead author Dr. Indra Narang, respirologist and director of sleep medicine at The Hospital for Sick Children (SickKids), Toronto, Ontario.
Over long-term, gastric bypass surgery associated with higher rate of diabetes remission — Improvement in cardiovascular risk factors – Severely obese patients who had Roux-en-Y gastric bypass surgery had significant weight loss that was sustained for an average of 6 years after the surgery and also experienced frequent remission and lower incidence of diabetes, hypertension, and abnormal cholesterol levels, compared to participants who did not have the surgery.
Obesity and metabolic syndrome associated with impaired brain function in adolescents – Metabolic syndrome (MetS) is associated with cognitive and brain impairments in adolescents and calls for pediatricians to take this into account when considering the early treatment of childhood obesity. As childhood obesity has increased in the U.S., so has the prevalence of metabolic syndrome ? a constellation of three or more of five defined health problems, including abdominal obesity, low HDL (good cholesterol), high triglycerides, high blood pressure and pre-diabetic insulin resistance.
Chronic stress linked to high risk of stroke — ‘Type A’ personality and life stressors boost risk independently of lifestyle factors – Chronic stress, prompted by major life stressors and type A personality traits, is linked to a high risk of stroke. Chronic stress, manifested as physical and/or mental symptoms in response to stressors lasting longer than 6 months has been linked to a heightened risk of heart disease. But its impact on the risk of stroke has not been clear.
