FDA-approved drug restores hair in patients with alopecia areata — Alopecia areata is a common autoimmune disease that causes disfiguring hair loss – Researchers have identified the immune cells responsible for destroying hair follicles in people with alopecia areata, a common autoimmune disease that causes hair loss, and have tested an FDA-approved drug that eliminated these immune cells and restored hair growth in a small number of patients.
NIH-funded researchers show possible trigger for MS nerve damage — Results of study in mice may lead to new treatments – High-resolution real-time images show in mice how nerves may be damaged during the earliest stages of multiple sclerosis. The results suggest that the critical step happens when fibrinogen, a blood-clotting protein, leaks into the central nervous system and activates immune cells called microglia.
Multiple sclerosis research doubles number of genes associated with the disease — Critical insight provided into the disease mechanisms behind multiple sclerosis – Scientists have identified 29 new genetic variants linked to multiple sclerosis, providing key insights into the biology of a very debilitating neurological disease. Many of the genes implicated in the study are relevant to the immune system, shedding light onto the immunological pathways that underlie the development of multiple sclerosis.
Study shows RA patients and doctors differ on disease severity assessment — Depressed patients showed highest level of discord in evaluating their disease – A novel study by researchers at the University of California, San Francisco found that nearly one-third of Rheumatoid Arthritis (RA) patients differed from their physicians in assessment of their disease severity.
Indian spice may delay liver damage and cirrhosis — Curcumin improves sclerosing cholangitis in Mdr2 -/- mice by inhibition of cholangiocyte inflammatory response and portal myofibroblast proliferation – Curcumin, one of the principal components of the Indian spice turmeric, seems to delay the liver damage that eventually causes cirrhosis, suggests preliminary experimental research in the journal Gut.
Blood test can predict rheumatoid arthritis before symptoms arise — Study confirms elevated cytokine levels are early indicator of disease – Researchers from University Hospital in Umea, Sweden, have identified several cytokines, cytokine-related factors, and chemokines that increase significantly prior to rheumatoid arthritis (RA) disease onset.
Found: A gene that may play a role in type 1 diabetes – Stanford University’s researchers have identified a gene that may play a role in the development of type 1 diabetes, an autoimmune disease in which the immune system attacks the body’s insulin-producing cells.
Aussie and Kiwi researchers make double MS genetic discovery – 2 new locations of genes causing multiple sclerosis. – Two new locations of genes responsible for multiple sclerosis are discovered which will help to unravel the causes of MS and other autoimmune disease, revealed by Australian and New Zealand researchers