Bariatric surgery lowers nonalcoholic fatty liver disease

Bariatric surgery or gastric sleeve surgery approache is found highly effective for reducing nonalcoholic fatty liver disease, emphasised in a study published in the Annals of Internal Medicine.

The trial included 100 patients in Norway with type 2 diabetes and obesity who were randomly assigned to undergo either gastric bypass or gastric sleeve surgery.

Both procedures led to substantial reduction in hepatic steatosis at 5 weeks and an almost complete clearance of liver fat 1 year after surgery.

Investigators previously showed that Roux-en-Y gastric bypass (RYGB) was superior to sleeve gastrectomy for type 2 diabetes remission.

All patients in the RYGB group and 94% in the sleeve gastrectomy group had no or low-grade steatosis.

The liver fibrosis findings were less conclusive.

Enhanced liver fibrosis test scores increased for 69% of patients and 1 in 5 patients progressed to a higher grade of fibrosis.

Further research is warranted on long-term fibrosis progression or regression.

The researchers will observe participants for an additional 5 years.

Source: American Medical Association.

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