Lung cancer cells’ survival gene 14-3-3zeta seen as drug target

Lung cancer cells’ survival gene 14-3-3zeta seen as drug target, as lung cancer cells can?t survive on their own when this key gene called 14-3-3zeta is silenced. – One of the deadliest forms of cancer appears to carry a specific weakness. When a key gene called 14-3-3zeta is silenced, lung cancer cells can’t survive on their own, researchers have found.

Novel anti-cancer strategy moves to clinic

Emory University researchers have developed a novel anti-tumor compound that represents a distinct strategy: targeting one of the most important “intercept points” for cancer cells. – Researchers at Emory University have developed a novel anti-tumor compound that represents a distinct strategy: targeting one of the most important “intercept points” for cancer cells.

Obese pregnant women give birth to heavier babies

New study suggests that maternal body composition at or near conception has important implications for offspring?s obesity, and obesity during conception phase may set the stage for offspring?s obesity risk. – The number of overweight and obese Americans continues to grow rapidly. Today, 50 percent of adults are overweight and up to 20 percent are obese. While the number of overweight/obese children is at an all time high, the steady increase of overweight infants ? individuals under 11 months old ? is alarming.

GIP hormone to prevent obesity

Gastric inhibitory polypeptide (GIP) hormone in the body is capable of promoting weight loss, improving insulin resistance and reversing diabetes. – A new study finds that a chemical found in the body is capable of promoting weight loss, improving insulin resistance and reversing diabetes in an animal model. The hormone is gastric inhibitory polypeptide (GIP) receptor blockade.

TV prescription drug ads minimize risk information

Prescription drug ads on television still do not present a fair balance of information, especially when it comes to the risk of side effects. – A new University of Georgia study finds that most of prescription drug ads on television still do not present a fair balance of information, especially when it comes to the risk of side effects.

Impact of Gastroesophageal reflux disease on survival

In this population-based study, reflux symptoms were not associated with worse survival. The vast majority of heartburn sufferers can be reassured of the benign nature of their condition. – Gastroesophageal reflux disease (GERD), often known as acid reflux, is a common problem that has been associated with cancers, asthma, recurrent aspiration and pulmonary fibrosis. A new study published in The American Journal of Gastroenterology examines whether GERD sufferers may have shorter lifespans than those without the disease.

New strategies work to put cancer on the firing line

Cancer cells are our own cells gone awry. That means our immune system doesn?t always see cancer as a horrific invader. – Dr. Yukai He wants to put cancer in the bull’s eye. “Cancer really comes from us,” the Medical College of Georgia Cancer Center immunologist says of the scary reality that cancer cells are our own cells gone awry. That means our immune system doesn’t always see cancer as a horrific invader.

MRI for better assessment of liver fibrosis

Chronic liver disease and cirrhosis remains a major public health problem worldwide. While the majority of complications from chronic liver disease result from progressive hepatic fibrosis, the available diagnostic tests used in clinical practice are not sensitive or specific enough to detect occult liver injury at early or intermediate stages. – MRI imagery is emerging as a non-invasive way to determine the existence and extent of hepatic fibrosis. It could eventually help the development of pharmacologic strategies to combat the condition.

Older surgical patients at greater risk for developing cognitive problems

Patients over the age of 60 who have elective surgeries such as joint replacements, hysterectomies and other non-emergency, inpatient procedures, are at an increased risk for long-term cognitive problems, according to a new study led by Duke University Medical Center researchers. – Duke University Medical Center researchers reveal that the patients over the age of 60 who have elective surgeries such as joint replacements, hysterectomies and other non-emergency, inpatient procedures, are at an increased risk for long-term cognitive problems.

Siglec-8 protein a possible key to allergy and asthma control

Activating a protein found on some immune cells seems to halt the cells? typical job of spewing out substances that launch allergic reactions, a study by Johns Hopkins researchers suggests. – Johns Hopkins researchers suggests in a study that activating a protein found on some immune cells seems to halt the cells’ typical job of spewing out substances that launch allergic reactions.