Diabetes duration and advancing age independently predict diabetes complications

Duration of diabetes and advancing age independently predict diabetes complications, risk of death – The duration of diabetes and advancing age independently predict diabetes severity and risk of death in older adults with type 2 diabetes. In a new study led by Kaiser Permanente and the University of Chicago, researchers investigated contemporary rates of diabetes complications and risk of death then contrasted them across categories of age and duration of diabetes.

Actual pandemic flu death toll was much higher in 2009

2009 Pandemic Flu Death Toll Much Higher Than Official Worldwide Estimates – A research team consisting of more than 60 collaborators in 26 countries has estimated the global death toll from the 2009 outbreak of the H1N1 virus to be 10 times higher than the World Health Organization’s count, which was based on laboratory-confirmed cases of this flu.

Regular physical activity in later life boosts healthy aging sevenfold

Regular physical activity in later life boosts likelihood of ‘healthy aging’ up to sevenfold — Helps stave off major ill health and dementia even for those getting started relatively late – It’s never too late to get physically active, with even those starting relatively late in life reaping significant health benefits, reveals researchers. Four years of sustained regular physical activity boosted the likelihood of healthy ageing sevenfold compared with consistent inactivity.

Genetic changes cause low metabolic rate and obesity

Novel genetic mutations cause low metabolic rate and obesity — Researchers believe the gene could be a useful therapeutic target for treating obesity and type 2 diabetes – Gene changes can reduce basal metabolic rate – how the body burns calories, and thereby cause severe obesity, revealed by researchers from the University of Cambridge, UK. Researchers believe this gene could be a useful therapeutic target for treating obesity and type 2 diabetes.

A good night’s rest may literally clear the mind

Brain may flush out toxins during sleep — NIH-funded study suggests sleep clears brain of damaging molecules associated with neurodegeneration – Using mice, researchers showed for the first time that the space between brain cells may increase during sleep, allowing the brain to flush out toxins that build up during waking hours. These results suggest a new role for sleep in health and disease.

Botox Cosmetic approved to improve crow’s feet lines

US FDA approves Botox Cosmetic to improve the appearance of crow’s feet lines – A new use for Botox Cosmetic (onabotulinumtoxinA) for the temporary improvement in the appearance of moderate to severe lateral canthal lines, known as crow’s feet, in adults is approved in USA. Botox Cosmetic is the only FDA approved drug treatment option for lateral canthal lines.

Parkinson’s Biomarker Test has prognostic and diagnostic value in Parkinson’s Disease

Comprehensive Parkinson’s Biomarker Test Has Prognostic and Diagnostic Value, Penn Medicine Team Reports — First Biomarker Results from Parkinson’s Progression Markers Initiative Detect Differences in Subtypes of Parkinson’s Disease – The first biomarker results reported from the Parkinson’s Progression Markers Initiative (PPMI), showing that a comprehensive test of protein biomarkers in spinal fluid have prognostic and diagnostic value in early stages of Parkinson’s disease.

Pazopanib better than sunitinib in advanced kidney cancer

Pazopanib shows better quality-of-life in advanced kidney cancer – Two oral targeted drugs — Pazopanib (Votrient) and sunitinib (Sutent) — approved for metastatic kidney cancer worked equally well, but one proved superior in tolerability, the safety profile and many measures of quality of life favored pazopanib.

Tamiflu drug resistance in H7N9 flu cases raises concern

Tamiflu Resistance Confirmed in H7N9 Flu Cases — Drug resistance in new China bird flu raises concern – Resistance easily develops when patients take antiviral drugs such as oseltamivir (tamiflu) for treating h7n9 influenza infections. Researcher’s analysis, which includes 14 patients who were hospitalized in Shanghai within 2 days of starting therapy with Tamiflu, appears in The Lancet.

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