Cancer drug bortezomib ? used to treat multiple myeloma – effectively treats organ transplant rejections. – University of Cincinnati (UC) researchers have discovered a new therapy for transplant patients, targeting the antibody-producing plasma cells that can cause organ rejection.
New evidence may explain why it is that we lose not only our youthful looks, but also our youthful pattern of gene activity with age. – Researchers have discovered that DNA damage decreases a cell’s ability to regulate which genes are turned on and off in particular settings. This mechanism, which applies both to fungus and to us, might represent a universal culprit for aging.
Children’s Hospital of Pittsburgh of UPMC Study Demonstrates Unique Form of Bone Marrow Transplant Can Cure Sickle Cell Disease – A unique approach to bone marrow transplantation pioneered in part by a Children’s Hospital of Pittsburgh of UPMC physician has proven to be the only safe and effective cure for sickle cell disease, according to a new study.
In US, diabetic patients have nearly doubled their spending on drugs for the diabetes disease in last 6 years. – Because of the increased number of patients, growing reliance on multiple medications and the shift toward more expensive new medicines, the annual cost of diabetes drugs nearly doubled in only six years, rising from $6.7 billion in 2001 to $12.5 billion in 2007 according to a study in the Oct. 27, 2008, issue of the Archives of Internal Medicine.
Living Cell Technologies receives New Zealand’s Health Minister?s approval to start leading edge live cell therapy clinical trial in New Zealand for Diabetes patients. – Living Cell Technologies Limited (ASX: LCT; OTCQX: LVCLY) announced that New Zealand Health Minister, the Honorable David Cunliffe, has approved an application from the company to conduct in New Zealand a Phase I/IIa clinical trial of DiabeCell?, LCT’s lead product candidate for the treatment of insulin dependent (Type 1) diabetes.
US FDA issues Interim Safety and Risk Assessment of Melamine and Melamine-related Compounds in Food. – The U.S. Food and Drug Administration (FDA) issued the results of its interim safety and risk assessment of melamine and melamine-related compounds in food, including infant formula.
Three genes are associated with increased risk of higher levels of uric acid in the blood, which can lead to gout. – Researchers have identified two new genes ? and confirmed the role of a third gene ? associated with increased risk of higher levels of uric acid in the blood, which can lead to gout, a common, painful form of arthritis.
Gastric bypass results in substantial weight loss in most patients. Diabetes and larger pouch size are independently associated with poor weight loss after GBP. – Individuals with diabetes and those whose stomach pouches are larger appear less likely to successfully lose weight after gastric bypass surgery, according to a report in the September issue of Archives of Surgery, one of the JAMA/Archives journals.
High-dose injections of vitamin C may reduce tumor weight and growth rate by about 50 percent of brain, ovarian, and pancreatic cancers, – High-dose injections of vitamin C, also known as ascorbate or ascorbic acid, reduced tumor weight and growth rate by about 50 percent in mouse models of brain, ovarian, and pancreatic cancers, researchers from the National Institutes of Health (NIH) report in the August 5, 2008, issue of the Proceedings of the National Academy of Sciences.
The availability of new antiretroviral drugs and formulations, including drugs in new classes, and recent data on treatment choices for antiretroviral-naive and -experienced patients warrant an update of the International AIDS Society?USA guidelines for the use of antiretroviral therapy in adult human immunodeficiency virus (HIV) infection. – An evaluation of recent data has led to an update in the guidelines and recommendations for antiretroviral treatment of adult human immunodeficiency virus (HIV) infection, according to an article in the August 6 issue of JAMA, a theme issue on HIV/AIDS.
The U.S. Food and Drug Administration (FDA) has notified manufacturers of fluoroquinolone antimicrobial drugs that a Boxed Warning in the product labeling concerning the increased risk of tendinitis and tendon rupture is necessary. – The U.S. Food and Drug Administration (FDA) requests boxed warnings on fluoroquinolone antimicrobial drugs. FDA seeks this to strengthen warnings concerning increased risk of tendinitis and tendon rupture.
Female who receive a kidney from a male donor are more likely to reject the kidney or graft, suggested by the Swiss researchers. – There are more chances of kidney rejection in a woman who gets a kidney from a male donor, revealed by Swiss researchers in a research paper published in the current issue of the medical journal The Lancet from UK.
