Selective reporting of antidepressant trials may have adverse consequences
Evidence-based medicine is valuable to the extent that the evidence base is complete and unbiased. Selective publication of clinical trials ? and the outcomes within those trials ? can lead to unrealistic estimates of drug effectiveness and alter the apparent risk?benefit ratio. – Selective publication in reporting results of antidepressant trials exaggerates the effectiveness of the drugs, and may have adverse consequences for researchers, study participants, health care professionals, and patients, revealed in a new study.