Named for the Greek word psora meaning “itch,” psoriasis is a chronic, non-contagious disease characterized by inflamed lesions covered with silvery-white scabs of dead skin. Psoriasis affects the skin and joints, and is believed to be an immune-mediated disease.
Stress may activate immune cells in the skin, resulting in inflammatory skin disease. – Current research suggests that stress may activate immune cells in your skin, resulting in inflammatory skin disease. The related report by Joachim et al., “Stress-induced Neurogenic Inflammation in Murine Skin Skews Dendritic Cells towards Maturation and Migration: Key role of ICAM-1/LFA-1 interactions,” appears in the November issue of The American Journal of Pathology.
US FDA Approves Updated Labeling for Psoriasis Drug Raptiva by Genentech; Safety concerns drove labeling changes. – The U.S. Food and Drug Administration announced labeling changes, including a Boxed Warning, to highlight the risks of life-threatening infections, including progressive multifocal leukoencephalopathy (PML), with the use of Raptiva (efalizumab).
Etanercept (Enbrel) significantly reduces psoriasis disease severity in children and adolescents with moderate-to-severe plaque psoriasis. – A Phase 3 study showed that children and adolescents with moderate to severe plaque psoriasis who received treatment with Enbrel experienced significant improvements in the signs and symptoms of their disease psoriasis.
UF scientists are testing the safety of experimental drug Compstatin for vision loss in macular degeneration patients. – University of Florida UF scientists are testing the safety of experimental drug Compstatin for vision loss in macular degeneration patients. In a first-of-its-kind safety research study, University of Florida researchers have injected an anti-inflammatory compound into the eye of a person with a sight-robbing disease.
People with a severe form of the skin disease psoriasis are likely to die at a younger age than their healthy peers, according to a study at the University of Pennsylvania School of Medicine, Philadelphia. – Patients with severe psoriasis appear to have an increased risk of death compared with patients without the skin condition, according to a report in the December issue of Archives of Dermatology, one of the JAMA/Archives journals.
