Cancer of the rectum is the disease characterized by the development of malignant cells in the lining or epithelium of the rectum. Malignant cells have changed such that they lose normal control mechanisms governing growth. These cells may invade surrounding local tissue or they may spread throughout the body and invade other organ systems.
Colonoscopy still the definitive test for colorectal cancer screening and prevention. – Death from colorectal cancer is highly preventable with effective screening and early detection. Many screening options are available, each with advantages and disadvantages, but half of eligible patients still do not participate in colorectal cancer screening.
About one-third of colorectal cancers are inherited, but the genetic cause of most of these cancers is unknown. The genes linked to colorectal cancer account for less than 5 percent of all cases. – Scientists at Northwestern University’s Feinberg School of Medicine and colleagues have discovered a genetic trait that is present in 10 to 20 percent of patients with colorectal cancer. The findings strongly suggest that the trait is a major contributor to colorectal cancer risk and likely the most common cause of colorectal cancer to date.
There may be a way to directly create cancer stem cells in the lab so you don?t always have to purify these rare cells from patients in order to study them directly. – With a bit of genetic trickery, researchers at the Stanford University School of Medicine have turned normal skin cells into cancer stem cells, a step that will make these naturally rare cells easier to study.
Anti-inflammatory drugs like aspirin may reduce breast cancer by up to 20 per cent, according to an extensive review carried out by experts at London?s Guy?s Hospital – Anti-inflammatory drugs like aspirin may reduce breast cancer by up to 20 per cent, according to an extensive review carried out by experts at London’s Guy’s Hospital and published in the March issue of IJCP, the International Journal of Clinical Practice.
New guidelines update recommendations on colorectal cancer screening, strong preference for tests that can prevent colon cancer, including colonoscopy. – A new guideline on colorectal cancer screening released by an expert group representing a broad spectrum of health care organizations, including the American College of Gastroenterology (ACG), the American Society for Gastrointestinal Endoscopy (ASGE) and the American Cancer Society (ACS), offers recommendations for various alternatives for colorectal cancer detection and states a strong preference for screening tests that can prevent colorectal cancer.
Consuming more than 18 ounces, or a little over a pound, of red meat (pork, beef, lamb and goat) each week can significantly increase a person?s risks for developing colorectal cancer. – For most Americans, meals tend to center around meat. To significantly decrease a person’s risks of developing colorectal cancer, experts at The University of Texas M. D. Anderson Cancer Center suggest a new approach to meal planning that focuses more on fruit and vegetable dishes.
The American College of Gastroenterology is committed to national policy changes to improve access to colorectal screening and increased use of these proven prevention strategies. – New data revealing decreasing trends in cancer deaths in the United States overall, and in colorectal cancer deaths in particular, highlight the remarkable benefits of colorectal cancer screening tests, but the lifesaving potential of these tests is unrealized for many Americans, according to experts from the American College of Gastroenterology.
Uninsured or Medicaid-insured patients are far more likely to be diagnosed with an advanced stage cancer than those with private insurance, according to a new American Cancer Society study of 3.5 million cancer patients with 12 of the most common cancer types. – A new American Cancer Society study of twelve types of cancer among more than 3.5 million cancer patients finds uninsured patients were significantly more likely to present with advanced stage cancer compared to patients with private insurance.
Avado Study of Avastin Plus Docetaxel Chemotherapy Showed Improved Progression-Free Survival in Patients With Advanced Breast Cancer – Genentech, Inc. (NYSE: DNA) announced that AVADO, a Roche-sponsored Phase III, placebo-controlled study evaluating Avastin? (bevacizumab) in combination with docetaxel chemotherapy met its primary endpoint of prolonging progression-free survival (PFS) in patients who had not received prior chemotherapy for their locally recurrent or metastatic HER2-negative breast cancer.
University of Pennsylvania School of Medicine researchers found that patients who received telephone mentoring from a trained “peer coach” were two times more likely to keep their first colonoscopy appointment than those who received an educational brochure about the procedure in the mail or received no peer or literature support. – Patients who have had a colonoscopy can play a life-saving role by encouraging other patients to follow through with their own colorectal cancer screenings, according to new research from the University of Pennsylvania School of Medicine. These peer coaches can provide important information to combat myths and fears that serve as barriers to colonoscopy ? issues patients say their doctors often fail to address.
R. Scott Braithwaite, M.D., and his colleagues developed a new method of evaluating medical screening tests like colonoscopy, called the “payoff time,” which is the minimum amount of time it takes for the benefits from a test to exceed its harms (i.e., its complications and side effects).
– Even though current guidelines advocate colorectal cancer screenings for those with severe illnesses, they may bring little benefit and may actually pose harm, according to a recent study by Yale School of Medicine researchers published in the Archives of Internal Medicine.
