Schizophrenia – a Molecular Explanation for Schizophrenia

Toward a Molecular Explanation for Schizophrenia — TAU researchers find inhibition of a basic cellular process may contribute to the mysterious disease – Surprisingly little is known about schizophrenia. It was only recognized as a medical condition in the past few decades, and its exact causes remain unclear. Since there is no objective test for schizophrenia, its diagnosis is based on an assortment of reported symptoms.

Rare genetic disorder linked to schizophrenia

Rare genetic disorder points to molecules that may play role in schizophrenia — Finding may suggest novel therapeutic target for treating disease – Scientists studying a rare genetic disorder have identified a molecular pathway that may play a role in schizophrenia. The findings may one day guide researchers to new treatment options for people with schizophrenia ? a devastating disease that affects approximately 1 percent of the world’s population.

RISPERDAL and Risperidone Tablets recalled due to odor of TBA

Ortho-McNeil-Janssen Pharmaceuticals, Inc. Voluntarily Recalls One Lot of RISPERDAL? Tablets and One Lot of Risperidone Tablets – Ortho-McNeil-Janssen Pharmaceuticals, Inc. is initiating a voluntary recall of one lot of RISPERDAL? (risperidone) 3mg Tablets, marketed by Janssen Division of Ortho-McNeil-Janssen Pharmaceuticals, Inc. and one lot of risperidone 2mg Tablets, marketed by Patriot Pharmaceuticals, LLC, a wholly owned subsidiary of Ortho-McNeil-Janssen Pharmaceuticals, Inc.

Antipsychotic drugs may lead to brain loss in schizophrenia patients

Antipsychotics for Schizophrenia Associated With Subtle Loss in Brain Volume – Patients with schizophrenia who take antipsychotic medications appear to lose a small but measurable amount of brain tissue over time, according to a report in the February issue of Archives of General Psychiatry.

Blood flows differently through the brains of schizophrenic patients

Blood flows differently through the brains of schizophrenic patients – Researchers in Germany have used a magnetic resonance imaging (MRI) technique called continuous arterial spin labeling (CASL) to map cerebral blood flow patterns in schizophrenic patients quickly and without using radiation or contrast agents. Their findings appear in the online edition and July printed issue of the journal Radiology.

Schizophrenia linked to common genetic variations

Schizophrenia linked for first time to chromosome region in study led by Stanford scientists — Schizophrenia and bipolar disorder share genetic roots. – Researchers has discovered that nearly a third of the genetic basis of schizophrenia may be attributed to the cumulative actions of thousands of common genetic variants.

Cancer – a concern in schizophrenia patients

Study finds cancer is the second most frequent cause of death in individuals with schizophrenia – Schizophrenia patients are four times as likely to die from all causes and are 50 percent more likely to die from cancer compared to people in the general population, revealed by researchers.

Substance abuse increases crime risk in schizophrenia patients

Substance Abuse Appears To Be an Important Factor in Increased Risk of Violent Crime By Persons With Schizophrenia – The increased risk of persons with schizophrenia committing violent crime may be largely mediated by co-existing substance abuse problems, according to a study in the May 20 issue of JAMA.

Fanapt iloperidone approved for schizophrenia treatment

FDA Approves Vanda Pharmaceuticals’ Fanapt(TM) for the Treatment of Schizophrenia – Vanda Pharmaceuticals Inc. (Nasdaq: VNDA) announced that the US Food and Drug Administration (FDA) has granted marketing approval of Fanapt (iloperidone) for the acute treatment of adult patients with schizophrenia.

Chromosomal changes increase schizophrenia risk

Schizophrenia may be partly caused by the effects of unusual structural changes in genes. – People with schizophrenia (mental illness variously affecting behavior, thinking, and emotion) have an increased number of unusual chromosomal changes, particularly structural changes that have the potential to alter the function of the genes.

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