Malarial parasite plasmodium vivax more serious

A strain of malaria thought previously to be ?benign? has been found to be potentially fatal in a recent study. – Plasmodium vivax can cause severe malaria associated with substantial morbidity and mortality, show two studies published in PLoS Medicine this week. These findings challenge the current dogma that P. falciparum can be severe and life-threatening whereas Plasmodium vivax tends to be mild, according to the related commentary by Stephen Rogerson (University of Melbourne, Australia), an expert not connected with these studies.

Infected female malaria mosquitoes more attracted to human odour

Unlocking the manipulation of mosquitoes by malaria parasites – Female mosquitoes infected with malaria parasites are significantly more attracted to human odour than uninfected mosquitoes. This was demonstrated in a laboratory setting in which infected female Anopheles gambiae sensu stricto mosquitoes were attracted to human odours three times more than mosquitoes that were not infected with the malaria-causing Plasmodium falciparum parasite.

Malaria during pregnancy first trimester – antimalarial is safe

Malaria during pregnancy first trimester – antimalarial is safe

Malaria during pregnancy: New study assesses risks during first trimester — Antimalarial drugs safer for pregnant women than disease – The malaria disease significantly increases the risk of miscarriage, but that treating with antimalarial drugs is relatively safe and reduces this risk in pregnant women expecting their new born babies.

A pre existing malaria infection can prevent a second infection

Malaria against malaria: A pre-existing malaria infection can prevent a second infection — Study will be published in Nature Medicine this Sunday, May 15, and may have impact in the fight against the disease – A team of researchers have found that pre-existing malaria prevents secondary infection by another Plasmodium strain, the parasite responsible for malaria, by restricting iron availability in the liver of the host.

Genes identified causing antimalarial drug resistance

Researchers identify genes causing antimalarial drug resistance – Using a pair of powerful genome-search techniques, researchers from the Harvard School of Public Health (HSPH), Harvard University, and the Broad Institute have identified several genes that may be implicated in the malaria parasite’s notorious ability to rapidly evade drug treatments.

Novel antimalarial drug candidate identified

New antimalarial drug candidate with novel mechanism of action has the potential to rapidly clear a Plasmodium infection upon administration of a single oral dose, as published in Science – Novartis announced that scientists at the Novartis Institute for Tropical Diseases (NITD), in collaboration with researchers from the Genomics Institute of the Novartis Research Foundation (GNF), the Swiss Tropical and Public Health Institute and The Scripps Research Institute have discovered a novel compound that shows promise as a next generation treatment for drug resistant malaria.

New treatment targets for malaria released

Scientists release data on potential new treatment targets for malaria – International collaboration led by St. Jude Children’s Research Hospital scientists identifies promising compounds for anti-malarial drug development and launches a database to share findings, advance fight against a leading killer of the world’s children

Egyptian pharaoh King Tutankhamun died of malaria

Study examines family lineage of King Tut, his possible cause of death – Malaria and bone abnormalities appear to have contributed to the death of Egyptian pharaoh King Tutankhamun, revealed by researchers.

125.2 million pregnant women at risk of malaria

Quantifying the number of pregnancies at risk of malaria in 2007: A demographic study – Research published this week in PLoS Medicine concludes that at least 125.2 million women at risk of malaria become pregnant each year.

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