Genome is the total genetic content contained in a haploid set of chromosomes in eukaryotes, in a single chromosome in bacteria, or in the DNA or RNA of viruses.
Research provides new kidney cancer clues — Gene is mutated in 1 in 3 patients with common form of renal cancer – Researchers have identified a gene that is mutated in one in three patients with the most common form of renal cancer. The identification of a frequently mutated gene will provide new insights into the biology of the disease.
GM chickens that don’t transmit bird flu developed – Breakthrough could prevent future bird flu epidemics – Chickens genetically modified to prevent them spreading bird flu have been produced by researchers at the Universities of Cambridge and Edinburgh. They developed a new gene coding that controls bird flu virus progress.
Genetic variants may affect the risk of breast cancer in women with BRCA2 mutations – An international study led by researchers at Memorial Sloan-Kettering Cancer Center has identified genetic variants in women with BRCA2 mutations that may increase or decrease their risk of developing breast cancer.
Largest genetic study of asthma points towards better treatments — Genetic variants increase susceptibility to asthma – An international study looking at DNA from over 26,000 people has identified several genetic variants that substantially increase susceptibility to asthma in the population.
New antimalarial drug candidate with novel mechanism of action has the potential to rapidly clear a Plasmodium infection upon administration of a single oral dose, as published in Science – Novartis announced that scientists at the Novartis Institute for Tropical Diseases (NITD), in collaboration with researchers from the Genomics Institute of the Novartis Research Foundation (GNF), the Swiss Tropical and Public Health Institute and The Scripps Research Institute have discovered a novel compound that shows promise as a next generation treatment for drug resistant malaria.
New genomic marker for tuberculosis may help identify patients who will develop the disease — Study highlights how blood profiling techniques could change patient care – It may soon be possible to identify patients who will develop tuberculosis, as scientists have identified changes in the blood specific to the disease.
First genetic link to common migraine exposed — Genetic variant may increase susceptibility to migraine triggers – Researchers have produced new insights into the triggers for migraines attacks. They have identified the first-ever genetic risk factor associated with common types of migraine.
New Parkinson’s gene is linked to immune system – A hunt throughout the human genome for variants associated with common, late-onset Parkinson’s disease has revealed a new genetic link that implicates the immune system and offers new targets for drug development.
Cigarette smoke causes harmful changes in the lungs even at the lowest levels — First study to show alteration in the function of genes in the lungs resulting from secondhand and low-level smoking – Casual smokers may think that smoking a few cigarettes a week is “no big deal.” But according to new research from physician-scientists at NewYork-Presbyterian Hospital/Weill Cornell Medical Center, having an infrequent smoke, or being exposed to secondhand smoke, may be doing more harm than people may think.
Scientists identify 95 genetic variants associated with cholesterol, triglycerides – Researchers have discovered or confirmed 95 regions of the human genome where genetic variants are associated with blood cholesterol and triglyceride levels, which are major indicators of heart disease risk.
Study evaluates association of genetic factors and brain imaging findings in Alzheimer’s disease – By investigating the association between genetic loci related to Alzheimer’s disease and neuroimaging measures related to disease risk, researchers may have uncovered additional evidence that several previously studied genetic variants are associated with the development and progression of Alzheimer’s disease and also may have identified new genetic risk factors for further study, according to a report in the June issue of Archives of Neurology, one of the JAMA/Archives journals.
Autism genome project identifies genetic variants that may make people susceptible to disorder – Autism is caused in part by rare genetic changes called copy number variants (CNVs), revealed by an international consortium of researchers from more than 70 universities, including the University of Utah.
