Pesticides, chemicals, vitamin E linked to diabetes

New associations between diabetes, environmental factors found by novel Stanford analytic technique – Researchers at the Stanford University School of Medicine suggests that one should begin looking suspiciously at other aspects of life – like past exposure to certain pesticides or chemicals and even one form of vitamin E. This may lead to diabetes.

New gene linked to Alzheimer’s disease

New gene associated with increased risk of Alzheimer’s disease – Researchers have identified a gene that appears to increase a person’s risk of developing late-onset Alzheimer’s disease, the most common type of Alzheimer’s disease.

Bone marrow can harbor HIV infected cells

University of Michigan scientists discover bone marrow can harbor HIV-infected cells — Targeting these reservoirs of latent cells may open door to new treatments – University of Michigan scientists have identified a new reservoir for hidden HIV-infected cells that can serve as a factory for new infections. This indicate a new target for curing the disease so those infected with the virus may someday no longer rely on AIDS drugs for a lifetime.

Genomic sequencing of difficult breast cancers

Life Technologies, TGen and US Oncology partner on groundbreaking breast cancer sequencing research — First-of-its-kind project will sequence difficult breast cancers to provide insight into treatment strategies – Life Technologies Corporation (NASDAQ: LIFE) announced that it is collaborating with the Translational Genomics Research Institute (TGen) and US Oncology to sequence the genomes of 14 patients afflicted with triple negative breast cancer whose tumors have progressed despite multiple other therapies.

Virus hybridization could create pandemic bird flu

Virus hybridization could create pandemic bird flu – Genetic interactions between avian H5N1 influenza and human seasonal influenza viruses have the potential to create hybrid strains combining the virulence of bird flu with the pandemic ability of H1N1, according to a new study.

Creating personalized biomarkers from tumor DNA to treat cancer

Personalizing cancer: Creating biomarkers from tumor DNA – Researchers have developed a new technique for tracking cancer by identifying personalized biomarkers from tumor DNA, reports a new study in the 24 February 2010 issue of the journal Science Translational Medicine, published by AAAS, the nonprofit science society.

Genes found linked to breast cancer drug resistance

Genes found linked to breast cancer drug resistance could guide future treatment choices – Researchers at Dana-Farber Cancer Institute have discovered a gene activity signature that predicts a high risk of cancer recurrence in certain breast tumors that have been treated with commonly used chemotherapy drugs.

Two new genes identified causing ankylosing spondylitis

UT rheumatologists advance genetic research related to disabling form of arthritis – Work done in part by researchers at The University of Texas Health Science Center at Houston has led to the discovery of two new genes that are implicated in ankylosing spondylitis (AS), an inflammatory and potentially disabling disease.

Gene linked to aggressive form of prostate cancer

Genetic variant associated with aggressive form of prostate cancer – Researchers at Wake Forest University Baptist Medical Center and colleagues have identified the first genetic variant associated with aggressive prostate cancer, proving the concept that genetic information may one day be used in combination with other factors to guide treatment decisions.

H1N1 influenza severity linked to Streptococcus pneumoniae

Severity of H1N1 influenza linked to presence of Streptococcus pneumoniae – The presence of the Streptococcus pneumoniae in samples that can be easily obtained in clinics and emergency rooms may predict risk of severe disease in H1N1 pandemic influenza.

Leprosy susceptibility genes reported in a genome study

Leprosy susceptibility genes reported in New England Journal of Medicine paper — Largest genome-wide association study of an infectious disease – In the first genome-wide association study (GWAS) of leprosy and the largest GWAS on an infectious disease, scientists at the Genome Institute of Singapore (GIS) and 26 institutes in China identified seven genes that increase an individual’s susceptibility to leprosy.

Embryonic stem cell lines lack genetic diversity

University of Michigan (U-M) study reveals lack of diversity in embryonic stem cell lines – The most widely used human embryonic stem cell lines lack genetic diversity, a finding that raises social justice questions that must be addressed to ensure that all sectors of society benefit from stem cell advances, according to a University of Michigan research team.

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