Immune system | Page 21 of 22

Genes linked with lupus giving hope for new treatments

Researchers have made a number of important new discoveries into the mysterious autoimmune disease lupus. A consortium of international researchers has located new regions of the human genome associated with an increased risk for the disease. – Scientists have identified a number of genes involved in Lupus, a devastating autoimmune disease, in new research published today in the journal Nature Genetics. In an international genetic study of more than 3,000 women, researchers found evidence of an association between Lupus (systemic lupus erythematosus or SLE) and mutations in several different genes.

Studies highlight MRSA evolution and resilience

A single strain of an evolving bacterium has been responsible for most of the community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) infections. – Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) infections are caused primarily by a single strain-USA300-of an evolving bacterium that has spread with “extraordinary transmissibility” throughout the United States during the past five years, according to a new study led by National Institutes of Health (NIH) scientists. CA-MRSA, an emerging public health concern, typically causes readily treatable soft-tissue infections such as boils, but also can lead to life-threatening conditions that are difficult to treat.

Intelence, etravirine HIV Drug approved in US

The U.S. Food and Drug Administration approved etravirine tablets for the treatment of HIV infection in adults who have failed treatment with other antiretrovirals. Etravirine is a non-nucleoside reverse transcriptase inhibitor (NNRTI) that helps to block an enzyme which HIV needs to multiply. – US FDA approved Tibotec Therapeutics’ Intelence, etravirine tablets for the treatment of HIV infection, to be used in combination with other anti-HIV medications, in adults who have failed treatment with other antiretrovirals.

Immune system can help heal patients with heart failure

The ability to change or modulate the patient?s immune response has now been shown to be attainable as well as successful in treating certain stages of heart failure. – Modifying the immune system of a patient with heart failure reduces the patient’s risk of death and the need for hospitalization, according to research published in recent edition of The Lancet.

Newly discovered virus linked to skin cancer

A new strategy to hunt for human viruses described in this week?s issue of the journal Science by the husband-and-wife team who found the cause of Kaposi’s sarcoma has revealed a previously unknown virus strongly associated with another rare but deadly skin cancer called Merkel cell carcinoma. – Researchers using sequencing technique discovered a new cancer virus Merkel cell polyomavirus (MCV) causing Kaposi’s sarcoma, is associated with another rare but deadly skin cancer called Merkel cell carcinoma.

Enbrel, etanercept improved psoriasis in children and adolescents

Etanercept (Enbrel) significantly reduces psoriasis disease severity in children and adolescents with moderate-to-severe plaque psoriasis. – A Phase 3 study showed that children and adolescents with moderate to severe plaque psoriasis who received treatment with Enbrel experienced significant improvements in the signs and symptoms of their disease psoriasis.

AIDS drugs may prevent vaginal transmission of HIV

There are 33 million people infected with HIV. This study is a highly significant breakthrough because it offers proof-of-principle that pre-exposure prophylaxis with currently available anti-retroviral drugs can potentially prevent vaginal HIV transmission, empowering women throughout the world to protect themselves from this deadly disease. – Prescription drugs now used to treat human immunodeficiency virus infection in adults may prevent the vaginal transmission of HIV, researchers at UT Southwestern Medical Center have found.

273 human proteins required for HIV propagation

Using a technique called RNA interference to screen thousands of genes, researchers identified 273 human proteins required for HIV propagation. The vast majority had not been connected to the virus by previous studies. – Current drugs attack HIV itself, leaving patients vulnerable to counterattack by the rapidly mutating virus, which often evolves resistance. But the human proteins exploited by HIV represent potential therapeutic targets that could avoid this problem. The challenge will be to develop drugs that inhibit HIV by interacting with these human proteins without hurting our cells.

Protein may trigger insulin production in diabetic patients

University of Florida researchers have coaxed liver and pancreatic cells within diabetic mice into churning out insulin by injecting the animals with a naturally occurring protein called Pdx1, opening up a new research avenue that someday could lead to safer treatments for type 1 diabetes. Pdx1 activates the genes controlling the development of the pancreas cells that make and release insulin to maintain safe levels of glucose in the body. – If the human body were a stage, then proteins would rank among the lead actors in the play we call “Life.” These large biological molecules hold many starring roles, and their lines are dictated by information encoded in our genes. They are production powerhouses, regulating the basic processes of living and controlling countless functions. Many are enzymes that produce or use energy. Others regulate genes.

Quick Test For Drug-Resistant Staph Infections MRSA

The U.S. Food and Drug Administration (FDA) approved the first rapid blood test for the drug-resistant staph bacterium known as MRSA (methicillin-resistant Staphylococcus aureus). – The U.S. Food and Drug Administration (FDA) announced it has cleared for marketing the first rapid blood test for the drug-resistant staph bacterium known as MRSA (methicillin-resistant Staphylococcus aureus), which can cause potentially deadly infections.