Violence puts wear and tear on kids’ DNA — Exposure to Violence During Childhood is Associated with Telomere Erosion from 5 to 10 Years of Age – Children who have experienced violence might really be older than their years. The DNA of 10-year-olds who experienced violence in their young lives has been found to show wear and tear normally associated with aging, a Duke University study has found.
Mayo Clinic launches whole genome breast cancer study – The Breast Cancer Genome Guided Therapy Study (BEAUTY Project) will help physicians tailor chemotherapy to breast cancer patients based on their individual genomes and the genomes of their tumors.
Mutations in 3 genes linked to autism spectrum disorders – Mutations in three new genes have been linked to autism, according to new studies including one with investigators at Mount Sinai School of Medicine. All three studies include lead investigators of the Autism Sequencing Consortium (ASC).
Drug-proof ‘pig MRSA’ makes leap from livestock to humans — Pig-to-Human ‘Superbug’ May Be Due to Animal Antibiotics – A strain of methicillin-resistant Staphylococcus aureus (MRSA) bacteria that humans contract from livestock was originally a human strain, but it developed resistance to antibiotics once it was picked up by farm animals. The findings illustrate a very close link between antibiotic use on the farm and potentially lethal human infections.
New gene study of ADHD points to defects in brain signaling pathways — Children’s Hospital of Philadelphia research suggests that interventions at the glutamate transmission level might treat ADHD disorder – Pediatric researchers analyzing genetic influences in attention-deficit/hyperactivity disorder (ADHD) have found alterations in specific genes involved in important brain signaling pathways.
TGen breast cancer research benefits from $3.5 million Komen award — Grant enables multi-institute team to study rare and aggressive type of breast cancer – The Translational Genomics Research Institute (TGen) is part of a team of medical investigators receiving a $3.5 million grant from Susan G. Komen for the Cure to study triple-negative breast cancer, a highly aggressive form of this cancer that disproportionately affects African-Americans.
Salmonella Kentucky has developed resistance to antibiotic Ciprofloxacin – A strain of Salmonella resistant to the most powerful antibiotics has been found in the UK, France and Denmark. This particular strain has a high level of resistance to ciprofloxacin, a common treatment for severe salmonella infections.
Research discovers genetic link to Barrett’s esophagus, esophageal cancer — 5-year study identifies genes that predispose for BE/EAC – Mutations in three genes have been identified that are more prevalent in patients with esophageal cancer and Barrett esophagus, a premalignant metaplasia (change in cells or tissue) caused by chronic gastroesophageal reflux disease (GERD), according to preliminary research reported in the July 27 issue of JAMA.
Swiss-US team finds indigenous cases of leprosy in the Southern United States — Study confirms human contamination through contact with armadillos – Using advanced DNA analysis and extensive field work, an international research team has confirmed the link between leprosy infection in Americans and direct contact with armadillos.
Protein levels could signal that a child will develop diabetes – Decreasing blood levels of a protein that helps control inflammation may be a red flag that could help children avoid type 1 diabetes, researchers say.
