Researchers identify genes causing antimalarial drug resistance – Using a pair of powerful genome-search techniques, researchers from the Harvard School of Public Health (HSPH), Harvard University, and the Broad Institute have identified several genes that may be implicated in the malaria parasite’s notorious ability to rapidly evade drug treatments.
Research provides new kidney cancer clues — Gene is mutated in 1 in 3 patients with common form of renal cancer – Researchers have identified a gene that is mutated in one in three patients with the most common form of renal cancer. The identification of a frequently mutated gene will provide new insights into the biology of the disease.
New antimalarial drug candidate with novel mechanism of action has the potential to rapidly clear a Plasmodium infection upon administration of a single oral dose, as published in Science – Novartis announced that scientists at the Novartis Institute for Tropical Diseases (NITD), in collaboration with researchers from the Genomics Institute of the Novartis Research Foundation (GNF), the Swiss Tropical and Public Health Institute and The Scripps Research Institute have discovered a novel compound that shows promise as a next generation treatment for drug resistant malaria.
Animal study reveals new target for antidepressants – University of Michigan scientists have provided the most detailed picture yet of a key receptor in the brain that influences the effectiveness of serotonin-related antidepressants, such as Prozac.
New gene associated with increased risk of Alzheimer’s disease – Researchers have identified a gene that appears to increase a person’s risk of developing late-onset Alzheimer’s disease, the most common type of Alzheimer’s disease.
Researchers discover new approach for identifying smokers at highest risk for developing lung cancer – Researchers from Boston University School of Medicine (BUSM) in collaboration with investigators at the University of Utah, have discovered a new approach for identifying smokers at the highest risk for developing lung cancer.
Study examines family lineage of King Tut, his possible cause of death – Malaria and bone abnormalities appear to have contributed to the death of Egyptian pharaoh King Tutankhamun, revealed by researchers.
Circumcision associated with significant changes in bacteria — Changes in bacteria within the penis microbiome documented for the first time. – Circumcision, which substantially lowers HIV risk in men, also dramatically changes the bacterial communities of the penis, according to a study led by scientists at the Translational Genomics Research Institute (TGen) and Johns Hopkins University and published Jan. 6 in the scientific journal PLoS ONE.
Leprosy susceptibility genes reported in New England Journal of Medicine paper — Largest genome-wide association study of an infectious disease – In the first genome-wide association study (GWAS) of leprosy and the largest GWAS on an infectious disease, scientists at the Genome Institute of Singapore (GIS) and 26 institutes in China identified seven genes that increase an individual’s susceptibility to leprosy.
CSIR completes first ever Human Genome Sequencing in India – The Council of Scientific and Industrial Research (CSIR) has achieved completion of first ever Human Genome Sequencing in India. Scientist of CSIR at the Institute of Genomics and Integrative Biology (IGIB), Delhi have sequenced the Human Genome of an anonymous healthy Indian citizen.
